Reference values for healthy human myocardium using a T1 mapping methodology: results from the International T1 Multicenter cardiovascular magnetic resonance study

Table 2 T1 values per age, gender and contrast dose

	1.5 T	3 T	1.5 T	3 T	Sig.
	(n = 110)	(n = 105)	(n = 92)	(n = 87)	(p-value)
Age categories
	Native T1 (msec)		ECV
Group 1	952 ± 22	1053 ± 26	0.24 ± 0.03	0.24 ± 0.02
Group 2	953 ± 25	1057 ± 24	0.25 ± 0.04	0.25 ± 0.03
Group 3	957 ± 25	1058 ± 25	0.24 ± 0.03	0.24 ± 0.04
Group 4	965 ± 18	1052 ± 24	0.23 ± 0.04	0.23 ± 0.03
Sig. (p-value)	F = 1.30, p = 0.28	F = 1.16, p = 0.21	F = 1.09, p = 0.46	F = 1.11, p = 0.36
Gender	Native T1 (msec)		ECV
Males	955 ± 23	1053 ± 25	0.23 ± 0.04	0.24 ± 0.05
Females	957 ± 23	1054 ± 25	0.25 ± 0.03	0.25 ± 0.05
Sig. (p-value)	0.44	0.87	0.36	0.78

Age groups were determined per quartiles: group 1: ≤30 years (1.5 T, n = 27, 3 T = 26), group 2: 31 and 42 years (1.5 T, n = 28, 3 T = 27); group 3: 42 and 53 years (1.5 T, n = 27, 3 T = 24), group 4: ≥ 53 years (1.5 T, n = 28; 3 T = 28). Student t-test or one-way ANOVA, P < 0.05 is considered significant.

ISSN: 1532-429X