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Table 1 Baseline clinical characteristics of severe AS patients and normal controls

From: Adenosine stress native T1 mapping in severe aortic stenosis: evidence for a role of the intravascular compartment on myocardial T1 values

  Severe aortic stenosis (n = 26) Normal controls (n = 16) P value
Age (years) 67.8 ± 9 63.3 ± 3.4 0.06
Male, n (%) 19 (73) 8 (53) 0.16
Past medical history, n (%)    
Hypertension 10 (38) -  
Diabetes 4 (15) -  
Medications, n (%)    
Metformin 4 (15) -  
ACE-I/ARB-II 7 (27) -  
Beta-blockers 5 (19) -  
Body mass index (kg/m2) 27.8 ± 4.5 27.0 ± 3.8 0.38
Systolic blood pressure (mmHg) 134.4 ± 18.1 131.0 ± 11.0 0.51
Diastolic blood pressure (mmHg) 74.4 ± 9.4 76.5 ± 10.2 0.51
Heart rate (bpm) 66.1 ± 9.4 64.3 ± 10.5 0.58
Peak AV gradient (mmHg)* 83.1 ± 14.6 -  
CMR findings    
Aortic valve area (cm2) 0.82 ± 0.02 4.04 ± 0.75 <0.001
LV end-diastolic volume (ml) 143.2 ± 44.4 133.7 ± 33.1 0.47
LV ejection fraction (%) 74.5 ± 5.8 68.8 ± 6.4 0.005
LV mass index (g/m2) 96.0 ± 31.2 55.8 ± 13.9 <0.001
Presence of LGE, n (%) 21 (81) 0 <0.001
Myocardial T1 (ms) 1196 ± 47 1168 ± 27 0.037
  1. Values are mean ± SD or percentages. ACE indicates angiotensin-converting enzyme-inhibitors; ARB, angiotensin-receptor antagonist-II; LGE, CMR, cardiovascular magnetic resonance; late gadolinium enhancement; LV, left ventricular.
  2. *Based on echocardiogram.