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Table 2 Means and standard errors of CMR parameters derived from dynamic venous oximetry, arterial velocimetry and pulse-wave velocity measurements, as well as inter-group differences

From: Effects of age and smoking on endothelial function assessed by quantitative cardiovascular magnetic resonance in the peripheral and central vasculature

Metrics

Y

O

NS

S

YNS

YS

ONS

OS

Differences (%)

O-Y

S-NS

ONS-YNS

YS-YNS

OS-ONS

Dynamic oximetry

Overshoot (%HbO 2 )

18.5±0.97

13.8±0.99

17.0±0.97

15.2±1.05

19.9±1.50

17.1±1.28

14.0±1.35

13.4±1.31

–25.6***

–10.7

–29.4**

–13.7

–4.4

Upslope (%HbO 2 /s)

3.34±0.17

2.43±0.17

3.33±0.16

2.39±0.18

3.74±0.21

2.86±0.25

2.89±0.24

1.94±0.22

–27.2***

–28.4***

–22.7**

–23.6**

–33.0**

Washout time (s)

9.53±0.38

10.6±0.39

9.37±0.37

10.8±0.40

9.00±0.31

10.2±0.51

9.77±0.44

11.4±0.84

11.1

15.3**

8.6

13.5*

16.3

Dynamic velocimetry

Pulse ratio

3.09±0.08

3.51±0.08

3.32±0.08

3.28±0.08

3.09±0.13

3.08±0.10

3.55±0.10

3.47±0.11

13.5***

−1.2

14.9**

−0.5

−2.5

Hyperemic index

1.16±0.01

1.12±0.01

1.25±0.01

1.01±0.01

1.24±0.07

1.06±0.08

1.27±0.10

0.97±0.08

–3.9

–19.5**

2.1

–14.9

–23.4*

Forward flow time-T FF (s)

33.2±1.66

30.8±1.62

33.1±1.6

30.2±1.68

34.7±2.06

30.3±2.22

31.5±2.35

30.2±2.57

–7.2

–8.7

–9.3

–12.8

–3.9

Pulse-wave velocity (m/s)

Aortic arch

8.16±0.25

9.37±0.24

8.46±0.25

9.16±0.26

7.94±0.27

8.46±0.35

8.98±0.32

9.77±0.44

14.8***

8.2

13.1*

6.5

8.8

Thoraco-abdominal

4.87±0.25

7.43±0.24

6.12±0.28

6.31±0.29

4.69±0.15

5.08±0.17

7.53±0.53

7.33±0.36

52.5***

3.0

60.7***

8.5

–2.6

Iliofemoral

6.78±0.21

8.08±0.21

7.31±0.22

7.57±0.23

6.72±0.24

6.79±0.23

7.91±0.26

8.26±0.43

19.2***

3.6

17.7**

1.0

4.5

Total

5.93±0.13

7.54±0.13

6.65±0.15

6.88±0.16

5.80±0.10

6.06±0.13

7.48±0.20

7.60±0.26

27.1***

3.5

29.0***

4.4

1.6

  1. Y = young subjects, O = older subjects, NS = non-smoking, S = smoking. Relative differences: ***P ≤ 0.001, **P ≤ 0.01, *P < 0.05.