Table 3 Cox Proportional Hazards Analysis for Future Events in Patients with ILD

Patients’ characteristics

Age, year

0.987

0.932 – 1.046

0.66

0.978

0.913 – 1.048

0.53

Male, yes

1.382

0.298 – 6.401

0.68

1.015

0.190 – 5.420

0.99

MRC dyspnea scale

1.660

0.938 – 2.937

0.082

Not selected

BMI, kg/m²

1.021

0.859 – 1.213

0.82

Not selected

Systolic BP, mmHg

1.018

0.981 – 1.056

0.35

Not selected

Diastolic BP, mmHg

1.021

0.970 – 1.074

0.43

Not selected

Heart rate, bpm

1.011

0.978 – 1.046

0.51

Not selected

Blood testing

BNP, pg/ml

1.000

0.997 – 1.002

0.88

Not selected

Creatinine, mg/dl

4.179

0.505 – 34.60

0.19

Not selected

KL-6, U/ml

1.000

0.999 – 1.001

0.40

Not selected

LDH, IU/l

1.003

0.991 – 1.015

0.63

Not selected

CRP, mg/dl

0.827

0.430 – 1.591

0.57

Not selected

Pulmonary function test

FVC, % predicted

0.996

0.967 – 1.025

0.77

Not selected

FEV1, % predicted

0.958

0.915 – 1.003

0.065

Not selected

D_LCO, % predicted

0.965

0.930 – 1.002

0.064

Not selected

6 min walk distance, m

0.995

0.985 – 1.005

0.35

Not selected

Right heart catheterization

mPAP, mmHg

1.003

0.956 – 1.051

0.913

Not selected

PCWP, mmHg

1.001

0.843 – 1.189

0.992

Not selected

Echocardiography

TAPSE, mm

0.863

0.727 – 1.024

0.092

Not selected

RVFAC, %

0.916

0.853 – 0.985

0.018

0.938

0.873 – 1.007

0.078

Cine CMR parameters

CMR derived RVEF, %

0.889

0.809 – 0.976

0.014

0.897

0.810 – 0.992

0.035