Fig. 3

Mean apparent magnetic susceptibility as a function of mean myofiber orientation in localized tissue regions. Myofiber orientation was calculated from the principal eigenvector of the DTI data (a). Each small ROI (n = 10 voxels) is outlined in yellow and represents myocardial fibers from one of three approximately orthogonal directions (represented by green, red, and blue). Magnetic susceptibility data were calculated from multi-orientation GRE image data and correlated with the fiber orientation. Each data point represents a measurement acquired from an individual specimen orientation. The results of the linear regression, as well as a 95 % confidence interval, are given for each region (b). The susceptibility anisotropy estimates (mean ± standard error) for each linear fit are shown. Error bars represent the standard deviations of each parameter within an individual ROI