Fig. 8
Comparison between experimental and simulated susceptibility anisotropy data. The experimental data were acquired from whole mouse myocardium specimens (n = 3) at 9.4 T, whereas the simulated data were calculated using the multi-filament model with two signal compartments (a). The simulated anisotropy of the intracellular compartment (b) is calculated by ignoring signal contributions from the extracellular compartment and using the fitted isotropic component (χ I ) and fixed anisotropic (χ A ) component values of the peptide group susceptibility tensor. The simulated anisotropy data are shown for when the model’s intracellular compartment contains both thick and thin filaments, thick filaments only, and thin filaments only. Error bars indicate the standard deviation of the experimental data