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Table 2 Key parameters of clinical 3D whole-heart first-pass perfusion literature

From: A review of 3D first-pass, whole-heart, myocardial perfusion cardiovascular magnetic resonance

Lead Author Year # of Patients CMR Centres CMR Observers Reference Standards QCA/% FFR/%
       Sensitivity Specificity Accuracy Sensitivity Specificity Accuracy
Manka [79] 2011 146 Single Single QCA 92 CI[85 99] 74 CI[64 85] 83 CI[76 89] N/A N/A N/A
Manka [125] 2012 120 Dual Single QCA & FFR 88 CI[77 95] 75 CI[61 83] 81 CI[73 88] 90 CI[82 98] 82 CI[71 94] 87 CI[80 93]
Jogiya [126] 2012 53 Single Dual† QCA & FFR 88 CI[71 96] 80 CI[56 93] 85 91 CI[75 98] 90 CI[66 98] 91 CI[83 95]
Jogiya [57] 2014 45 Single Single QCA & MPS‡ 94 CI[71 100] 81 CI[54 95] 88 N/A N/A N/A
Manka [130] 2015 150 Five Multiple QCA & FFR 77 CI[67 85] 94 CI[84 99] 83 CI[76 88] 85 CI[75 92] 91 CI[81 97] 87 CI[81 92]
  1. †3rd observer used when consensus could not be reached
  2. ‡For corresponding sensitivity, specificity and accuracy - see text
  3. CI = 95 % confidence interval