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Table 3 Hypertensives without versus Hypertensives with LVH

From: Extracellular volume quantification in isolated hypertension - changes at the detectable limits?

 

Hypertensives no LVH

Hypertensives with LVH

 
 

n = 26

n = 14

p-value

T1 mapping

T1 Blood (ms)

1564 ± 61

1614 ± 83

0.02

T1 Myocardium (ms)

948 ± 31

997 ± 27

<0.001

ECV by ShMOLLI (%)

26.2 ± 2.2

28.8 ± 2.8

<0.01

Clinical

Men

16 (62 %)

5 (35 %)

0.12

Age in years (IQR)

57.8 ± 12.2

53.2 ± 17.5

0.4

Height (cm)

171 ± 10.4

168.5 ± 6.1

0.44

Weight (kg)

86.6 ± 16.9

86.6 ± 13.8

1

Body surface area (m2)

2.02 ± 0.24

2.01 ± 0.18

0.79

Body mass index (kg/m2)

29.5 ± 4.7

30.4 ± 4.2

0.49

Systolic blood pressure (mmHg)

150.1 ± 18.0

155.5 ± 15.7

0.35

Diastolic blood pressure (mmHg)

87.1 ± 11.7

90.0 ± 8.4

0.35

eGFR (ml/min/1.73 m2)

83.6 ± 18.8

76.4 ± 24.2

0.23

Haematocrit (%)

0.43 ± 0.03

0.42 ± 0.05

0.39

Number of antihypertensives (0/1/2/3/4/5/6)

3/5/8/6/2/1/1

4/0/5/1/2/2/0

 

CMR

EDV index (ml/m2)

66.2 ± 11.7

82.5 ± 20.5

0.02

ESV index (ml/m2)

19.9 ± 7.2

29.4 ± 14.4

0.05

LVEF (%)

70.7 ± 7.3

65.9 ± 10.9

0.16

LAA index (cm/m2)

10.9 ± 2.1

13.3 ± 2.5

<0.01

Maximal wall thickness (mm)

10.9 ± 1.6

13.8 ± 2.6

<0.001

LV mass index (g/m2)

68.6 ± 11.8

112.4 ± 39.6

<0.001

LV mss/EDV (g/ml)

1.07 ± 0.26

1.41 ± 0.5

0.05

Transverse strain

34.0 ± 11.8

30.8 ± 9.4

0.21

Longitudinal strain

−18.7 ± 5.4

−17.4 ± 3.8

0.41

Circumferential strain

−24.7 ± 5.3

−24.6 ± 3.8

0.64

Radial strain

37.3 ± 13.1

35.4 ± 7.1

0.94

Late enhancement, n (%)

5 (19)

6 (43)

0.15

Electrocardiogram

Sokolov-Lyon index

22.3 ± 4.8

32.5 ± 13.1

<0.01

Cornell voltage criteria

13.7 ± 5.2

21.1 ± 8.7

<0.01

Aortic stiffness

Pulse wave velocity

7.7 ± 1.5

8.4 ± 1.6

0.15

Augmentation index

17.0 ± 5.7

13.6 ± 6.6

0.18

Aortic systolic blood pressure (mmHg)

141.5 ± 14.9

167.4 ± 27.2

<0.01

Aortic pulse pressure (mmHg)

54.6 ± 13.4

64.3 ± 17.2

0.13

Diastolic function on echocardiogram

E/A

0.9 ± 0.3

1.1 ± 0.5

0.7

E/e’ septal

10.3 ± 2.9

12.9 ± 7.3

0.36

E/e’ lateral

8.0 ± 2.3

12.9 8 ± 6.4

<0.01

Diastolic grade (I/II/III/IV)

3/18/5/0

0/6/7/1

<0.01