From: Extracellular volume quantification in isolated hypertension - changes at the detectable limits?
 | Hypertensives no LVH | Hypertensives with LVH |  |
---|---|---|---|
 | n = 26 | n = 14 | p-value |
T1 mapping | |||
T1 Blood (ms) | 1564 ± 61 | 1614 ± 83 | 0.02 |
T1 Myocardium (ms) | 948 ± 31 | 997 ± 27 | <0.001 |
ECV by ShMOLLI (%) | 26.2 ± 2.2 | 28.8 ± 2.8 | <0.01 |
Clinical | |||
Men | 16 (62Â %) | 5 (35Â %) | 0.12 |
Age in years (IQR) | 57.8 ± 12.2 | 53.2 ± 17.5 | 0.4 |
Height (cm) | 171 ± 10.4 | 168.5 ± 6.1 | 0.44 |
Weight (kg) | 86.6 ± 16.9 | 86.6 ± 13.8 | 1 |
Body surface area (m2) | 2.02 ± 0.24 | 2.01 ± 0.18 | 0.79 |
Body mass index (kg/m2) | 29.5 ± 4.7 | 30.4 ± 4.2 | 0.49 |
Systolic blood pressure (mmHg) | 150.1 ± 18.0 | 155.5 ± 15.7 | 0.35 |
Diastolic blood pressure (mmHg) | 87.1 ± 11.7 | 90.0 ± 8.4 | 0.35 |
eGFR (ml/min/1.73 m2) | 83.6 ± 18.8 | 76.4 ± 24.2 | 0.23 |
Haematocrit (%) | 0.43 ± 0.03 | 0.42 ± 0.05 | 0.39 |
Number of antihypertensives (0/1/2/3/4/5/6) | 3/5/8/6/2/1/1 | 4/0/5/1/2/2/0 | Â |
CMR | |||
EDV index (ml/m2) | 66.2 ± 11.7 | 82.5 ± 20.5 | 0.02 |
ESV index (ml/m2) | 19.9 ± 7.2 | 29.4 ± 14.4 | 0.05 |
LVEF (%) | 70.7 ± 7.3 | 65.9 ± 10.9 | 0.16 |
LAA index (cm/m2) | 10.9 ± 2.1 | 13.3 ± 2.5 | <0.01 |
Maximal wall thickness (mm) | 10.9 ± 1.6 | 13.8 ± 2.6 | <0.001 |
LV mass index (g/m2) | 68.6 ± 11.8 | 112.4 ± 39.6 | <0.001 |
LV mss/EDV (g/ml) | 1.07 ± 0.26 | 1.41 ± 0.5 | 0.05 |
Transverse strain | 34.0 ± 11.8 | 30.8 ± 9.4 | 0.21 |
Longitudinal strain | −18.7 ± 5.4 | −17.4 ± 3.8 | 0.41 |
Circumferential strain | −24.7 ± 5.3 | −24.6 ± 3.8 | 0.64 |
Radial strain | 37.3 ± 13.1 | 35.4 ± 7.1 | 0.94 |
Late enhancement, n (%) | 5 (19) | 6 (43) | 0.15 |
Electrocardiogram | |||
Sokolov-Lyon index | 22.3 ± 4.8 | 32.5 ± 13.1 | <0.01 |
Cornell voltage criteria | 13.7 ± 5.2 | 21.1 ± 8.7 | <0.01 |
Aortic stiffness | |||
Pulse wave velocity | 7.7 ± 1.5 | 8.4 ± 1.6 | 0.15 |
Augmentation index | 17.0 ± 5.7 | 13.6 ± 6.6 | 0.18 |
Aortic systolic blood pressure (mmHg) | 141.5 ± 14.9 | 167.4 ± 27.2 | <0.01 |
Aortic pulse pressure (mmHg) | 54.6 ± 13.4 | 64.3 ± 17.2 | 0.13 |
Diastolic function on echocardiogram | |||
E/A | 0.9 ± 0.3 | 1.1 ± 0.5 | 0.7 |
E/e’ septal | 10.3 ± 2.9 | 12.9 ± 7.3 | 0.36 |
E/e’ lateral | 8.0 ± 2.3 | 12.9 8 ± 6.4 | <0.01 |
Diastolic grade (I/II/III/IV) | 3/18/5/0 | 0/6/7/1 | <0.01 |