2D cine DENSE with low encoding frequencies accurately quantifies cardiac mechanics with improved image characteristics

Table 1 Summary statistics showed good agreement for all k_e between 0.04 and 0.10 cycles/mm. Larger biases, 95 % LoA, and CoVs were observed for k_e of 0.02 cycles/mm

E(k_e)**	Circumferential Strain (%)				Radial Strain (%)				Twist (Degrees)
E(k_e)**	Bias	95 % LoA	Mean CoV	p-value	Bias	95 % LoA	Mean CoV	p-value	Bias	95 % LoA	Mean CoV	p-value
E_0.10 – E_0.02	−1.9	±5.0	11 %	<0.01*	3.9	±20.4	23 %	0.11	−0.48	±1.92	14 %	0.04*
E_0.10 – E_0.04	−0.6	±3.6	6 %	0.15	−0.0	±15.9	14 %	1.00	−0.14	±1.22	8 %	0.32
E_0.10 – E_0.06	0.0	±3.2	6 %	0.91	0.8	±12.8	13 %	0.59	−0.22	±0.93	6 %	0.05
E_0.10 – E_0.08	0.1	±2.6	4 %	0.67	−0.5	±10.9	11 %	0.67	−0.13	±0.77	5 %	0.16
Inter-test	0.1	±2.0	4 %	0.53	0.9	±13.0	12 %	0.54	−0.05	±0.87	5 %	0.59

*Statistical significance between peak measures of mechanics using paired-sample t-test at significance level α = 0.05
**\( {E}_{\left[{\boldsymbol{k}}_{\boldsymbol{e}}\right]} \) represents peak strain or twist measured using a particular k_e
Abbreviations: LoA limits of agreement, CoV coefficient of variation

ISSN: 1532-429X