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Table 1 Cardiovascular magnetic resonance protocol for UK Biobank

From: UK Biobank’s cardiovascular magnetic resonance protocol

Description

Sagittal anatomy

Coronal and Transverse anatomy”

Long axis cines

Short axis cines

Aortic distensibility cine

Tagging

Coronal LVOT cine

Aortic valve flow

Native T1 map

Pulse sequence:

Simplified terminology (scientific terminology)

White blood CMR

(bSSFP)

White blood CMR

(bSSFP)

Cine CMR

(bSSFP)

Cine CMR

(bSSFP)

Cine CMR

(bSSFP)

Strain CMR

(GRE)

Cine CMR

(bSSFP)

Flow CMR

(GRE)

Parametric CMR

(ShMOLLI WIP780B)

Flip angle (°)

80

80

80

80

80

12

80

20

35

TR (ms)

2.6

2.6

2.7

2.6

2.8

8.2

2.7

4.6

2.6

TE (ms)

1.12

1.12

1.16

1.10

1.17

3.90

1.16

2.47

1.07

GRAPPA factor

2

2

2

2

2

0

2

2

2

Slice thickness (mm)

8.0

8.0

6.0

8.0

6.0

8.0

6.0

6.0

8.0

Slice gap (mm)

2.64

4

n.a.

2

n.a.

n.a.

n.a.

n.a.

n.a.

Typical Field of View (mm)

400 x400

400 x 400

380 x 274

380 x 252

380 x 294

350 x 241

380 x 384

340 x 340

360 x 236

Matrix

240 x 158

240 x 158

208 x 187

208 x 187

240 x 216

256 x 174

208 x 187

192 x 173

192 x 192

Voxel size

1.7 x 1.7 x 8.0

1.7 x 1.7 x 8.0

1.8 x 1.8 x 6.0

1.8 x 1.8 x 8.0

1.6 x 1.6 x 6.0

1.4 x 1.4 x 8.0

1.8 x 1.8 x 6.0

1.8 x 1.8 x 6.0

0.9 x 0.9 x 8.0

(Interpolation = On, factor 2)

Acquired temporal resolution (ms)

n.a.

n.a.

32.64

31.56

28.00

41.05

32.64

37.12

368.28

Calculated cardiac phases

1

1

50

50

50

1

50

30

1

ECG triggering/gating

PT

n.a.

RG

RG

RG

PT

RG

RG

PT

Other parameters

  

Inline Evaluation Ventricular Function

Inline Evaluation Ventricular Function

 

Grid spacing 6 mm, shared phases

  

T1 map determined on-line.

Image Filter

Off

Off

Off

Off

Off

Off

Off

Off

Off

Distortion Corr

On (2D)

On (2D)

On (2D)

On (2D)

On (2D)

On (2D)

On (2D)

On (2D)

Off

Raw Filter

Off

Off

Off

Off

Off

Off

Off

Off

On: Weak, slope 25

Elliptical filter

Off

Off

Off

Off

Off

Off

Off

Off

Off

No of breath-holds (expiration)

1

1

1 slice per breath-hold

1 slice per breath-hold

1

1 slice per breath-hold

1

1

1

Orientation

Sagittal (x11)

PE direction = AP

Coronal (x10), Transverse (x10)

PE direction = RL & AP

HLA, VLA, LVOT (sagittal) views

PE direction = varies

Coverage based to apex in SA views (approximately x10)

PE direction = AP

Transverse at level of pulmonary trunk/right pulmonary artery

PE direction = AP

SA views (b, m, a)

PE direction = AP

LVOT (coronal) view PE direction = RL

Aortic valve plane planned on both LVOT cines

PE direction = AP

SA (m)

PE direction = AP

Image example

  1. Abbreviations: bSSFP balanced steady state free precession, PT Prospective Triggering, RG Retrospective Gating, b basal, m midventricular, a apical, HLA Horizontal long axis, VLA Vertical Long Axis, LVOT Left Ventricular Outflow Tract, SA Short Axis