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Table 1 Cardiovascular magnetic resonance protocol for UK Biobank

From: UK Biobank’s cardiovascular magnetic resonance protocol

Description Sagittal anatomy Coronal and Transverse anatomy” Long axis cines Short axis cines Aortic distensibility cine Tagging Coronal LVOT cine Aortic valve flow Native T1 map
Pulse sequence:
Simplified terminology (scientific terminology)
White blood CMR
(bSSFP)
White blood CMR
(bSSFP)
Cine CMR
(bSSFP)
Cine CMR
(bSSFP)
Cine CMR
(bSSFP)
Strain CMR
(GRE)
Cine CMR
(bSSFP)
Flow CMR
(GRE)
Parametric CMR
(ShMOLLI WIP780B)
Flip angle (°) 80 80 80 80 80 12 80 20 35
TR (ms) 2.6 2.6 2.7 2.6 2.8 8.2 2.7 4.6 2.6
TE (ms) 1.12 1.12 1.16 1.10 1.17 3.90 1.16 2.47 1.07
GRAPPA factor 2 2 2 2 2 0 2 2 2
Slice thickness (mm) 8.0 8.0 6.0 8.0 6.0 8.0 6.0 6.0 8.0
Slice gap (mm) 2.64 4 n.a. 2 n.a. n.a. n.a. n.a. n.a.
Typical Field of View (mm) 400 x400 400 x 400 380 x 274 380 x 252 380 x 294 350 x 241 380 x 384 340 x 340 360 x 236
Matrix 240 x 158 240 x 158 208 x 187 208 x 187 240 x 216 256 x 174 208 x 187 192 x 173 192 x 192
Voxel size 1.7 x 1.7 x 8.0 1.7 x 1.7 x 8.0 1.8 x 1.8 x 6.0 1.8 x 1.8 x 8.0 1.6 x 1.6 x 6.0 1.4 x 1.4 x 8.0 1.8 x 1.8 x 6.0 1.8 x 1.8 x 6.0 0.9 x 0.9 x 8.0
(Interpolation = On, factor 2)
Acquired temporal resolution (ms) n.a. n.a. 32.64 31.56 28.00 41.05 32.64 37.12 368.28
Calculated cardiac phases 1 1 50 50 50 1 50 30 1
ECG triggering/gating PT n.a. RG RG RG PT RG RG PT
Other parameters    Inline Evaluation Ventricular Function Inline Evaluation Ventricular Function   Grid spacing 6 mm, shared phases    T1 map determined on-line.
Image Filter Off Off Off Off Off Off Off Off Off
Distortion Corr On (2D) On (2D) On (2D) On (2D) On (2D) On (2D) On (2D) On (2D) Off
Raw Filter Off Off Off Off Off Off Off Off On: Weak, slope 25
Elliptical filter Off Off Off Off Off Off Off Off Off
No of breath-holds (expiration) 1 1 1 slice per breath-hold 1 slice per breath-hold 1 1 slice per breath-hold 1 1 1
Orientation Sagittal (x11)
PE direction = AP
Coronal (x10), Transverse (x10)
PE direction = RL & AP
HLA, VLA, LVOT (sagittal) views
PE direction = varies
Coverage based to apex in SA views (approximately x10)
PE direction = AP
Transverse at level of pulmonary trunk/right pulmonary artery
PE direction = AP
SA views (b, m, a)
PE direction = AP
LVOT (coronal) view PE direction = RL Aortic valve plane planned on both LVOT cines
PE direction = AP
SA (m)
PE direction = AP
Image example
  1. Abbreviations: bSSFP balanced steady state free precession, PT Prospective Triggering, RG Retrospective Gating, b basal, m midventricular, a apical, HLA Horizontal long axis, VLA Vertical Long Axis, LVOT Left Ventricular Outflow Tract, SA Short Axis