Table 2 The minimum dataset from the CMR images analyzed manually in the first 5,000 CMR scans will be returned to the UK Biobank resources and will likely include
From: UK Biobank’s cardiovascular magnetic resonance protocol
Cardiovascular structure | Quantifiable parameters |
|---|---|
Left ventricle | Myocardial mass (g), ejection fraction (%), end-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml) and the corresponding values indexed to body surface area, height or weight. Time to peak contraction and filling rates (both in s) and peak contraction and filling rates (both in ml/s) can be derived from the cine images accepting the limitation of limited temporal resolution for this purpose. American Heart Association (AHA) myocardial segments: end-diastolic thickness (mm), end-systolic thickness (mm), thickening (mm), thickening (%). Strain (%) and strain-rates (%/s) in three directions (radial [ERR], circumferential [ECC] and longitudinal [ELL]) and in systole and diastole and corresponding changes in angle caused by shear (ERC and ECL). Torsion-rates (degrees/s). Midwall midventricular native T1 (ms). |
Right ventricle | Myocardial mass (g), ejection fraction (%), end-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml) and the corresponding values indexed to body surface area, height or weight |
Left atrium | End-diastolic area (cm2), end-systolic area (cm2) and left atrial diameters as typically measured by 2D- echocardiography approaches. Using the area length formula atrial volumes (ml), atrial stroke volume (ml) and atrial ejection fraction (%) can be derived. |
Right atrium | End-diastolic area (cm2), end-systolic area (cm2) and right atrial diameters as typically measured by 2D- echocardiography approaches. Using the area length formula atrial volumes (ml), atrial stroke volume (ml) and atrial ejection fraction (%) can be derived. |
Aorta | Distensibility (1/mmHg) in ascending aorta and proximal descending aorta; diastolic aortic dimensions (cm2): aortic root (annulus, sinus of valsalva, sinutubular junction) ascending aorta and proximal descending aorta. Diameter of abdominal aorta as visualized. |
Aortic valve | Peak velocity (cm/s), peak gradient (mmHg), forward volume (ml), regurgitant volume (ml), regurgitant fraction (%). Number of cusps of aortic valve (bicuspid, tricuspid, quadricuspid). |