From: Cardiac remodeling and dysfunction in childhood obesity: a cardiovascular magnetic resonance study
Obese/Overweight n = 41 | Healthy n = 29b | p value | p value, age adjusted | |
---|---|---|---|---|
Cardiac geometry | ||||
LV mass (g) | 92 ± 23 | 87 ± 29 | 0.45 | 0.001 |
LV mass index (g/m 2.7 ) | 27 ± 4 | 22 ± 3 | <0.001 | <0.001 |
LV end systolic volume (mL) | 51 ± 14 | 55 ± 19 | 0.47 | 0.36 |
LV end diastolic volume (mL) | 135 ± 30 | 141 ± 41 | 0.47 | 0.30 |
LV mass/volume ratio (dimensionless) | 0.68 ± 0.09 | 0.61 ± 0.05 | <0.001 | <0.001 |
Relative wall thickness (dimensionless) | 0.28 ± 0.04 | 0.26 ± 0.04 | 0.05 | 0.006 |
Average LV thickness (mm) | 5.6 ± 0.8 | 5.1 ± 0.8 | 0.01 | <0.001 |
Maximum LV thickness (mm) | 8.9 ± 1.3 | 8.0 ± 1.2 | 0.004 | <0.001 |
90 th percentile of LV thickness (mm) a | 7.4 ± 1.0 | 6.8 ± 1.0 | 0.01 | <0.001 |
Cardiac function | ||||
LV ejection fraction (%) | 62 ± 4 | 62 ± 4 | 0.98 | 0.51 |
E wave velocity (cm/s) | 61 ± 11 | 65 ± 13 | 0.17 | 0.16 |
A wave velocity (cm/s) | 28 ± 12 | 30 ± 13 | 0.51 | 0.52 |
E/A ratio (dimensionless) | 2.5 ± 1.0 | 2.5 ± 1.0 | 0.97 | 0.88 |
E’ (cm/s) | 12 ± 4 | 11 ± 2 | 0.78 | 0.93 |
E/E’ ratio (dimensionless) | 5.9 ± 2.9 | 5.9 ± 1.8 | 0.92 | 0.80 |