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Table 2 The optimized thresholds for detecting IPH

From: Semi-automatic carotid intraplaque hemorrhage detection and quantification on Magnetization-Prepared Rapid Acquisition Gradient-Echo (MP-RAGE) with optimized threshold selection

Data subset

AUC

Optimized threshold

 

IPH Area (mm2)a

n+/nb

SCM

Adjacent muscle

Median

SCM

Adjacent muscle

Median

With CA

>0

63/133

0.69

0.71

0.58

1.0

1.6

2.2

>1.25

52/122

0.71

0.72

0.64

1.0

1.6

2.2

>2.80

34/104

0.74

0.79

0.68

1.0

1.6

2.2

No CAc

>0

49/119

0.74

0.71

0.66

1.0

1.7

2.2

>1.25

40/110

0.76

0.71

0.72

1.0

1.7

2.2

>2.80

25/95

0.83

0.80

0.80

1.0

1.6

2.2

  1. AUC area under the ROC curve, IPH intraplaque hemorrhage, ROC Receiver operating characteristic, SCM sternocleidomastoid muscle
  2. aIPH area: excluding IPH with areas < π (0.63x)2, where 0.63 mm was the in-plane resolution of MP-RAGE, and x was set as 1 and 1.5 which gave areas of 1.25 and 2.80
  3. bn+: number of slices with IPH present in histology; n:total number of slices
  4. cNo CA: excluding heavily (>50 %) calcified IPH; with CA: not excluding heavily calcified IPH