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Table 1 CMR parameters of cardiac function

From: Cardiovascular magnetic resonance detects the progression of impaired myocardial perfusion reserve and increased left-ventricular mass in mice fed a high-fat diet

  Time (Weeks after start of diet)
6 weeks 12 weeks 18 weeks 24 weeks
Control HFD Control HFD Control HFD Control HFD
LVEDV (μL) 43 ± 7 42 ± 7 48 ± 9 47 ± 10 44 ± 7 40 ± 7 40 ± 6 43 ± 5
LVESV (μL) 17 ± 4 14 ± 4 17 ± 6 17 ± 6 16 ± 6 12 ± 5 13 ± 4 11 ± 5
LVEF (%) 61 ± 8 66 ± 8 64 ± 12 65 ± 8 64 ± 9 69 ± 12 67 ± 8 74 ± 11
Heart Rate (bpm) 530 ± 63 538 ± 88 478 ± 39 485 ± 69 450 ± 84 512 ± 62 507 ± 47 549 ± 59
Change in Heart Rate under Stress (%) 23 ± 16 28 ± 12 27 ± 5 16 ± 13 15 ± 19 21 ± 13 21 ± 28 −2 ± 15*
Ecc −0.14 ± 0.02 −0.13 ± 0.02 −0.13 ± 0.02 −0.12 ± 0.01 −0.12 ± 0.03 −0.11 ± 0.02 −0.12 ± 0.01 −0.14 ± 0.02
Ecc-subepi −0.09 ± 0.01 −0.09 ± 0.02 −0.09 ± 0.01 −0.08 ± 0.01 −0.08 ± 0.02 −0.07 ± 0.02 −0.08 ± 0.01 −0.09 ± 0.01
Ecc-subendo −0.19 ± 0.02 −0.17 ± 0.03 −0.18 ± 0.03 −0.16 ± 0.02 −0.17 ± 0.04 −0.16 ± 0.03 −0.17 ± 0.02 −0.20 ± 0.03
CURE 0.87 ± 0.06 0.85 ± 0.07 0.90 ± 0.05 0.87 ± 0.05 0.85 ± 0.06 0.89 ± 0.04 0.84 ± 0.04 0.84 ± 0.03
  1. *p < 0.05 vs. Control at same time point