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Table 4 Phase-contrast velocity mapping-based parameters

From: Early-stage heart failure with preserved ejection fraction in the pig: a cardiovascular magnetic resonance study

  Controls (n = 7) DOCA (n = 5) Controls vs. DOCA
Parameter Rest Stress p Rest Stress p prest pstress
Aortic vessel wall and aortic blood velocity
 APV (cm · s−1) 113 ± 15 158 ± 26 0.001 92 ± 14 140 ± 31 0.011 0.033 0.308
 AAmean (mm−2) 3.4 ± 0.4 3.7 ± 0.7 0.091 5.5 ± 0.5 5.0 ± 1.3 0.244 < 0.001 0.064
 AAmin (mm−2) 2.8 ± 0.4 3.0 ± 0.6 0.211 4.6 ± 0.5 4.2 ± 1.1 0.229 < 0.001 0.044
 AAmax (mm−2) 4.1 ± 0.4 4.5 ± 0.6 0.061 6.3 ± 0.5 5.7 ± 1.4 0.228 < 0.001 0.072
 AWT (mm) 1.8 ± 0.3    2.3 ± 0.4    0.039  
Transmitral and myocardial tissue velocities
 E (cm · s−1) 63 ± 6 78 ± 9 0.001 56 ± 10 70 ± 11 0.001 0.181 0.222
 A (cm · s−1) 47 ± 11 48 ± 9 0.714 43 ± 12 43 ± 13 0.801 0.532 0.404
 E/A 1.4 ± 0.5 1.7 ± 0.5 0.100 1.4 ± 0.4 1.7 ± 0.5 < 0.001 0.861 0.886
 AT (ms) 87 ± 17 79 ± 9 0.329 83 ± 14 70 ± 9 0.091 0.639 0.120
 DT (ms) 152 ± 50 163 ± 66 0.705 169 ± 67 153 ± 16 0.639 0.622 0.760
 E’sep (cm · s−1) 18 ± 4 20 ± 6 0.743 11 ± 3 14 ± 2 0.109 0.010 0.069
 E’lat (cm · s−1) 21 ± 5 25 ± 6 0.346 14 ± 3 16 ± 3 0.213 0.067 0.019
 E’ (cm · s−1) 20 ± 4 23 ± 6 0.492 13 ± 2 15 ± 2 0.130 0.007 0.025
 E/E’ 3.3 ± 0.6 3.6 ± 0.7 0.185 4.4 ± 1.1 4.6 ± 0.6 0.707 0.038 0.031
 (E/E’)/EDV (10−2 ml−1 · m2) 2.7 ± 0.5 3.1 ± 0.6 0.151 3.6 ± 0.9 4.8 ± 1.6 0.112 0.035 0.030
Pulmonary venous velocities
 S1 (cm · s−1) 33 ± 9 48 ± 4 0.006 39 ± 18 46 ± 5 0.516 0.502 0.408
 S2 (cm · s−1) 40 ± 10 49 ± 9 0.032 44 ± 18 44 ± 5 0.668 0.624 0.484
 D (cm · s−1) 37 ± 10 56 ± 11 < 0.001 57 ± 17 58 ± 6 0.792 0.035 0.636
 S/D 1.1 ± 0.2 0.9 ± 0.2 0.019 0.8 ± 0.2 0.8 ± 0.2 0.864 0.045 0.194
Coronary sinus
 NFVCS (ml · m−2) 1.6 ± 0.5 2.7 ± 1.0 0.003 2.4 ± 0.6 2.8 ± 0.5 0.300 0.025 0.886
 GMP (ml · min−1 · g−1) 1.6 ± 0.4 3.7 ± 1.4 0.002 1.9 ± 0.3 2.9 ± 0.5 0.029 0.197 0.268
 MPR   2.2 ± 0.5    1.5 ± 0.4    0.028
  1. APV aortic peak velocity, AA mean average aortic cross section area, AA min minimal aortic cross section area, AA max maximal aortic cross section area, AWT aortic wall thickness, E early diastolic transmitral peak velocity, A late diastolic transmitral peak velocity, E’ sept early diastolic septal wall mitral annular tissue velocity, E’ lat early diastolic lateral wall mitral annular tissue velocity, E’ average early diastolic mitral annular tissue velocity, S1 early systolic pulmonary venous peak velocity, S2 systolic pulmonary venous peak velocity, D early diastolic pulmonary venous peak velocity, S maximal systolic pulmonary venous peak velocity, NFV CS coronary sinus net forward volume, GMP global myocardial perfusion, MPR stress-to-rest myocardial perfusion reserve
  2. p is related to the rest-stress comparison within each group. prest and pstress relate to group comparisons at rest and stress, respectively