Journal of Cardiovascular Magnetic Resonance

Table 5 Septal values of native T1 and ECV within subgroups of the DMD cohort

From: Native T1 values identify myocardial changes and stratify disease severity in patients with Duchenne muscular dystrophy

Technique	Location	Measurement	Age < 14		Age > 14
Technique	Location	Measurement	Average	SD	Average	SD	p
MOLLI	Septal	Native T1	1054.69	32.04	1040.40	73.98	0.20
	Septal	ECV^a	27.57	4.40	28.04	6.49	0.67
SASHA	Septal	Native T1	1257.36	43.68	1217.37	74.60	<0.01
	Septal	ECV^a	23.74	2.43	23.44	5.23	0.71
			LVEF ^b > 55 %		LVEF ^b < 55 %
			Average	SD	Average	SD	p
MOLLI	Septal	Native T1	1040.32	37.79	1055.49	85.86	0.32
	Septal	ECV^a	26.81	4.13	29.40	7.39	0.06
SASHA	Septal	Native T1	1230.34	58.48	1238.84	78.02	0.58
	Septal	ECV^a	22.64	2.78	24.99	5.70	0.02
			LGE ^c -		LGE ^c +
			Average	SD	Average	SD	p
MOLLI	Septal	Native T1	1039.49	39.62	1050.62	71.69	0.33
	Septal	ECV^a	27.09	3.84	28.36	6.68	0.24
SASHA	Septal	Native T1	1223.85	55.55	1240.30	72.79	0.22
	Septal	ECV^a	23.06	2.93	23.89	5.03	0.31

Septal values of native T1 and ECV using the MOLLI and SASHA techniques for measuring T1 within subgroups of the DMD cohort divided into those < 14 years (n = 12), and those > 14 years (n = 8); divided again into those with LVEF > 55 % (n = 12) and LVEF < 55 % (n = 8); divided again into those with LGE (n = 8) and those without LGE (n = 12). There are few significant differences between the group, including only septal ECV using MOLLI and SASHA when the group is divided by LVEF, and native T1 when the group is divided by age.^a ECV extracellular volume fraction, ^bLVEF left ventricular ejection fraction, ^cLGE late gadolinium enhancement

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ISSN: 1532-429X

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