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Table 1 Demographics, Medical History, Biochemistry and CMR values for the CFVR population and the part also examined by PET (MBFR population)

From: Coronary microvascular function and myocardial fibrosis in women with angina pectoris and no obstructive coronary artery disease: the iPOWER study

 

CFVR population, n = 64

MBFR population, n = 54

 Age, mean (SD)

62.5 (8.3)

62.0 (7.5)

 Hypertension, n (%)

38 (59.4)

29 (53.7)

 Hyperlipidaemia, n (%)

42 (65.6)

34 (63)

 Family history of CAD, n (%)

36 (57.1)

30 (57)

 Smoking (current), n (%)

15 (23)

12 (22)

 Smoking (previous + current), n (%)

39 (61)

34 (63)

 Pack years (20 cig./day) · year)a, median (IQR)

27 (7;35)

29 (8;35)

 Stable angina pectoris, n (%)

45 (70.3)

39 (72)

 Postmenopausal status, n (%)

56 (89)

48 (89)

 Comorbidity, n (%)

38 (60)

31 (59)

 ESC’s HeartScore (% risk)b, mean (SD)

1.4 (1.2)

1.3 (1.3)

 Framingham risk scorec, mean (SD)

0.093 (0.05)

0.094 (0.06)

Biochemistry

 Total-cholesterol (mmol/l), mean (SD)

4.8 (1.0)

4.9 (1.1)

 LDL cholesterol (mmol/l), mean (SD)

2.7 (1.0)

2.8 (1.0)

 HDL cholesterol (mmol/l), mean (SD)

1.6 (0.5)

1.6 (0.5)

 Non-HDL cholesterol (mmol/l), mean (SD)

3.2 (1.0)

3.3 (1.0)

 Hematocrit, mean (SD)

40.5 (2.9)

40.7 (2.7)

Clinical Assessment

 Body mass index (kg/m2), median (IQR)

23.9 (21.9;28.3)

23.7 (22.0;27.9)

 Body mass index (kg/m2) > 25, n (%)

26 (41)

22 (40)

 Abdominal circumference (cm), mean (SD)

93.5 (12.4)

93 (12.5)

 Systolic blood pressure (mmHg), mean (SD)

148.1 (25.7)

146.5 (25.8)

 Diastolic blood pressure (mmHg), mean (SD)

85.5 (15.8)

85.6 (16.5)

 Heart rate at rest (bpm), mean (SD)

64.8 (10.3)

64.2 (11.1)

 Atherosclerosis at CAG, n (%)

29 (45)

24 (44)

Cardiac Magnetic Resonance (global values)

 Left ventricular ejection fraction (%), mean (SD)

59.6 (5.9)

59.7 (5.9)

 End systolic volume (ml), mean (SD)

60.6 (17.2)

61.1 (17.4)

 End diastolic volume (ml), mean (SD)

148.5 (27.0)

150.3 (27.8)

 Left ventricular mass index (g/m2), mean (SD)

48.38 (7.6)

49.1 /7.8)

 Left ventricular hypertrophy, n (%)

5 (8)

5 (10)

 Cardiac output, mean (SD)

5.7 (1.1)

5.7 (1.2)

 Stroke volume, mean (SD)

87.9 (15.3)

89.3 (16.1)

 Myocardial mass (diastole), mean (SD)

87.2 (17.8)

88.2 (18.8)

 Myocardial mass (systole), mean (SD)

92.6 (20.7)

92.9 (21.5)

Medication

 Beta Blockers, n (%)

23 (36)

19 (35)

 Acetylsalicylic acid, n (%)

35 (54.7)

29 (54)

 Statin, n (%)

35 (54.7)

28 (52)

 Calcium antagonists, n (%)

17 (27)

13 (25)

 Angiotensin conv. enzyme inhibitor, n (%)

8 (13)

7 (13)

 Angiotensin receptor blockers, n (%)

11 (18)

6 (11)

  1. aOnly including previous and current smokers. bEstimates absolute risk (%) for cardiovascular death within 10 years. cEstimates risk for coronary heart disease over a period of 10 years (1 = 100 % risk). CFVR coronary flow velocity reserve, MBFR myocardial blood flow reserve, IQR interquartile range, SD standard deviation, CAD coronary artery disease, LDL low-density-lipoprotein, HDL high-density-lipoprotein, non-HDL non-high-density-lipoprotein cholesterol, ESC European Society of Cardiology