Table 1 Baseline characteristics

Age, years

62 [51–71]

66 [55–73]

54 [48–63]

<0.001

Male sex, n (%)

600 (76)

389 (72)

211 (84)

<0.001

Body mass index, kg/m²

27 [25–30]

28 [25–31]

26 [24–29]

<0.001

 Current smoking, n (%)

339/724 (43)

194/482 (36)

145/242 (58)

<0.001

 Diabetes mellitus, n (%)

160/789 (20)

142/539 (26)

18/250 (7)

<0.001

 Hypercholesterolemia, n (%)

303/784 (38)

250/536 (46)

53/250 (21)

<0.001

 Family history for CAD, n (%)

268/611 (34)

177/407 (33)

91/204 (36)

0.79

Systolic blood pressure, mmHg

130 [117–147]

135 [119–150]

126 [114–140]

<0.001

Diastolic blood pressure, mmHg

80 [70–88]

80 [70–90]

80 [70–85]

0.07

Heart rate, beats/min

76 [67–87]

76 [68–88]

76 [65–85]

0.23

Time from symptom onset to PCI hospital admission, min

180 [109–310]

183 [110–311]

166 [104–306]

0.23

Door-to-balloon time, min

30 [22–42]

30 [23–42]

29 [20–42]

0.56

Previous infarction, n (%)

48/791 (6)

42/539 (8)

6/631 (2)

<0.01

Previous PPCI, n (%)

67 (9)

61 (11)

6 (2)

<0.001

Previous CABG, n (%)

11 (1)

11 (2)

0 (0)

0.02

Anterior infarction, n (%)

395/755 (50)

262/516 (49)

133/239 (53)

0.21

Killip-class on admission

0.52

 1, n (%)

696 (88)

472 (87)

224 (89)

 2, n (%)

59 (7)

42 (8)

17 (7)

 3, n (%)

20 (3)

16 (3)

4 (2)

 4, n (%)

17 (2)

10 (2)

7 (3)

Number of diseased vessels

<0.01

 1, n (%)

419 (53)

261 (48)

158 (63)

 2, n (%)

225 (28)

165 (31)

60 (24)

 3, n (%)

148 (19)

114 (21)

34 (14)

Infarct related artery

0.59

 Left anterior descending, n (%)

344 (43)

240 (44)

104 (41)

 Right coronary artery, n (%)

344 (43)

226 (42)

118 (47)

 Left circumflex, n (%)

97 (12)

68 (13)

29 (12)

 Left main, n (%)

5 (1)

4 (1)

1 (0)

 Bypass graft, n (%)

2 (0)

2 (0)

0 (0)

TIMI risk score

3 [2–5]

4 [2–5]

2 [2–4]

<0.001

TIMI-flow before PPCI

0.64

 TIMI-flow 0, n (%)

444 (56)

298 (55)

146 (58)

 TIMI-flow 1, n (%)

103 (13)

73 (14)

30 (12)

 TIMI-flow 2, n (%)

128 (16)

92 (17)

36 (14)

 TIMI-flow 3, n (%)

117 (15)

77 (14)

40 (16)

TIMI-flow after PPCI

0.38

 TIMI-flow 0, n (%)

12 (2)

9 (2)

3 (1)

 TIMI-flow 1, n (%)

19 (2)

14 (3)

5 (2)

 TIMI-flow 2, n (%)

61 (8)

47 (9)

14 (6)

 TIMI-flow 3, n (%)

699 (88)

469 (87)

230 (91)

Stent implanted, n (%)

774 (98)

527 (98)

247 (98)

0.60

Thrombectomy, n (%)

190 (24)

124 (23)

66 (26)

0.32

 Aspirin, n (%)

790 (100)

538 (100)

252 (100)

1.0

 ß-blockers, n (%)

757 (96)

519 (96)

238 (94)

0.19

 ACE-I/ARB, n (%)

751 (95)

515 (95)

236 (94)

0.21

 Statin, n (%)

749 (95)

508 (94)

241 (96)

0.47

 Aldosterone antagonist, n (%)

80 (10)

55 (12)

25 (10)

0.34