Table 2 CMR parameters according to age
From: Age and sex corrected normal reference values of T1, T2 T2* and ECV in healthy subjects at 3T CMR
Total population n = 75 | [20–30] n = 10 | [30-40] n = 9 | [40-50] n = 9 | [50-60] n = 11 | [60-70] n = 11 | [70-80] n = 20 | >or = 80 n = 5 | P value | ||
|---|---|---|---|---|---|---|---|---|---|---|
LV EDVi (ml/m2) | 79 ± 17 [48;119] | 98 ± 11ǂ*ε◊ [87;118] | 93 ± 14ε◊ [72;121] | 82 ± 12†ε◊ [60;102] | 78 ± 13†ε◊ [65;107] | 82 ± 15ε◊ [57;102] | 66 ± 12†¥ǂ*$ [46;91] | 59 ± 7†¥ǂ*$ [50;66] | <0.001 | |
LV ESVi (ml/m2) | 29 ± 9 [14;50] | 40 ± 7*$ε◊ [32;50] | 34 ± 8ε◊ [18;45] | 32 ± 8ε◊ [21;45] | 28 ± 7†◊ [18;42] | 29 ± 8†◊ [16;42] | 24 ± 6†¥ǂ [15;35] | 17 ± 5†¥ǂ*$ [11;25] | <0.001 | |
LV-EF (%) | 64 ± 6 [55;76] | 59 ± 3◊ [54;63] | 64 ± 5 [57;75] | 61 ± 5◊ [55;72] | 64 ± 6 [55;75] | 66 ± 6 [57;76] | 65 ± 4 [55;68] | 72 ± 6†ǂ [62;78] | 0.03 | |
LV mass i (g/m2) | 58 ± 11 [36;81] | 56 ± 9 [44;72] | 58 ± 9 [49;78] | 54 ± 15 [35;68] | 56 ± 7 [46;67] | 64 ± 12 [44;82] | 59 ± 13 [36;79] | 60 ± 11 [48;70] | 0.56 | |
Mass/Vol ratio (%) | 0.8 ± 0.2 [0.5;1.2] | 0.6 ± 0.05$ε◊ [0.5;0.7] | 0.6 ± 0.1ε◊ [0.5;0.8] | 0.7 ± 0.2 ε◊ [0.4;0.9] | 0.7 ± 0.1 ε◊ [0.6;0.8] | 0.8 ± 0.1†◊ [0.7;1.0] | 0.9 ± 0.1†¥ǂ* [0.7;1.2] | 1.0 ± 0.3†¥ǂ*$ [0.8;1.4] | <0.001 | |
RV-EDVi (ml/m2) | 82 ± 18 [52;132] | 104 ± 17ǂ*ε◊ [83;132] | 95 ± 17ε◊ [71;133] | 83 ± 12† [63;105] | 78 ± 12† [64;105] | 87 ± 18ε◊ [67;129] | 69 ± 12†¥$ [51;92] | 68 ± 11†¥$ [57;80] | <0.001 | |
RV-ESVi (ml/m2) | 35 ± 10 [19;63] | 47 ± 10ǂ*$ε◊ [35;64] | 40 ± 8ε◊ [26;55] | 37 ± 4†ε◊ [30;45] | 32 ± 8† [24;44] | 38 ± 8†ε◊ [25;52] | 28 ± 7†¥ǂ$ [16;40] | 25 ± 6†¥ǂ$ [19;34] | <0.001 | |
RV EF (%) | 58 ± 5 [48;68] | 55 ± 3*ε◊ [49;59] | 58 ± 4 [50;63] | 55 ± 2*ε◊ [52;58] | 59 ± 5†ǂ [49;67] | 57 ± 3◊ [52;63] | 59 ± 6†ǂ [47;75] | 63 ± 5†ǂ$ [56;66] | 0.007 | |
T1 (ms) | Whole myoc | 1122 ± 57 [977;1225] | 1070 ± 80$ε◊ [885;1149] | 1114 ± 43 [1038;1158] | 1100 ± 54 [990;1186] | 1132 ± 42 [1069;1188] | 1144 ± 51† [1089;1239] | 1141 ± 42 [1047;1223] | 1142 ± 64† [1042;1212] | 0.01 |
septum | 1162 ± 81 [954;1285] | 1066 ± 133 [768;1209] | 1141 ± 76 [987;1233] | 1142 ± 78 [991;1225] | 1182 ± 40 [1099;1232] | 1182 ± 60 [1108;1305] | 1196 ± 42 [1094;1266] | 1188 ± 75 [1081;1282] | 0.01 | |
ECV % | Whole myoc | 26.6 ± 3.2 [21.6;34.5] | 25.1 ± 1.7 [22.7;27.7] | 24.8 ± 1.9 [22.2;27.7] | 27.3 ± 4.3 [21.6;33.7] | 25.0 ± 1.9 [22.9;29.6] | 27.1 ± 4.6 [22.2;34.6] | 28.0 ± 2.6 [21.6;31.0] | 29.1 ± 1.3 [28.1;31.2] | 0.01 |
septum | 27.5 ± 3.8 [21.0;37.6] | 26.7 ± 1.3 [24.5;28.3] | 26.4 ± 4.2 [21.0;35.0] | 28.9 ± 6.0 [21.7;40.3] | 25.9 ± 1.9 [22.6;29.7] | 26.4 ± 4.2 [21.0;34.4] | 28.7 ± 3.8 [21.9;36.9] | 29.9 ± 1.8 [27.4;32.5] | 0.19 | |
T2 (ms) | Whole myoc | 52 ± 6 [41;61] | 53 ± 5 [48;62] | 52 ± 4 [46;56] | 53 ± 4 [46;58] | 55 ± 2 [52;58] | 53 ± 7 [43;60] | 52 ± 6 [42;63] | 43 ± 5 †¥ǂ*$ε [36;48] | 0.007 |
septum | 52 ± 7 [38;64] | 54 ± 4 [49;59] | 53 ± 4 [48;59] | 54 ± 4 [47;61] | 56 ± 4 [52;63] | 53 ± 9 [38;64] | 51 ± 6 [41;62] | 42 ± 5†¥ǂ*$ε [34;46] | 0.004 | |
T2* (ms) | Whole myoc | 24 ± 5 [12;33] | 23 ± 5 [14;30] | 26 ± 5 [20;34] | 21 ± 6 [13;30] | 21 ± 6 [10;29] | 24 ± 3 [19;27] | 25 ± 5 [13;32] | 28 ± 3 [26;32] | 0.27 |
septum | 25 ± 5 [11;39] | 27 ± 6 [22;39] | 26 ± 4 [22;31] | 23 ± 8 [11;39] | 22 ± 7 [11;31] | 24 ± 5 [16;35] | 25 ± 4 [19;35] | 28 ± 2 [24;31] | 0.38 | |