High-throughput gadobutrol-enhanced CMR: a time and dose optimization study

Table 1 Left ventricular (LV) structure and functional values obtained before (C-) and after (C+) injection of gadobutrol 0.1 mmol/kg body-weight using a cine-balanced steady state free precession (bSSFP) sequence and intra-observer agreement

	C+	C-		p-value	ICC*	Mean difference (LOA)
EDV (ml)	142.1 ± 39.8	138.4 ± 39.7	C+ vs. C-	0.008	0.980	3.7 ml (17.9, −10.4)
ESV (ml)	67.9 ± 29.5	65 ± 28.8		0.001	0.986	2.9 ml (10.8, −5.1)
SV (ml)	74.2 ± 17.1	73.4 ± 15.5		0.538	0.895	0.9 ml (15.6, −13.9)
EF (%)	53.8 ± 9.4	54.8 ± 8.8		0.095	0.935	−1% (5.3, −7.3)

Values expressed as mean ± SD; significant values are in bold; *p < 0.001 for all ICC values
EDV, End-diastolic volume, EF Ejection fraction, ESV End-systolic volume, LOA Limits of agreement, SV Stroke volume

ISSN: 1532-429X