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Table 1 Baseline characteristics of the patients who underwent CMR

From: Diagnostic and prognostic utility of cardiovascular magnetic resonance imaging in heart failure with preserved ejection fraction – implications for clinical trials

 

All

No new diagnoses group (n = 112)

New diagnoses group (n = 42)

p value

Demographics

 Age, years

72 ± 10

73 ± 9

72 ± 12

0.61

 Male

78 (50.6)

54 (48.2)

24 (57.1)

0.32

Clinical findings

 Atrial fibrillation

72 (46.8)

50 (44.6)

24 (52.4)

0.42

 Heart rate (bpm)

70 ± 14

70 ± 14

72 ± 16

0.57

 Systolic blood pressure (mmHg)

143 ± 25

144 ± 25

146 ± 26

0.61

 Diastolic blood pressure (mmHg)

74 ± 12

74 ± 12

74 ± 13

0.99

 Body mass index (kg/m2)

34 ± 7

34 ± 7

33 ± 9

0.66

NYHA

    

 I/II

106 (68.8)

77 (68.8)

29 (69.0)

0.97

 III/IV

48 (31.2)

35 (31.3)

13 (31.0)

Medical History

 Known coronary artery disease

32 (20.8)

 Hypertension

139 (90.3)

111 (89.3)

39 (92.9)

0.60

 Diabetes

75 (48.7)

54 (48.2)

21 (50.0)

0.88

 Chronic obstructive pulmonary disease or asthma

27 (17.5)

17 (15.2)

10 (23.8)

0.21

Chest radiography

 Pulmonary edema

110 (71.4)

79 (70.5)

31 (73.8)

0.69

Medication

 Aspirin

54 (35.1)

42 (37.5)

12 (28.6)

0.30

 Beta-blocker

99 (64.3)

74 (66.1)

25 (59.5)

0.45

 ACEi or ARB

130 (84.4)

97 (86.6)

33 (78.6)

0.22

 Statin

97 (63.0)

70 (62.5)

27 (64.3)

0.84

 Loop diuretic

125 (81.2)

91 (81.3)

34 (81.0)

0.97

Biochemistry

 Sodium (mmol/L)

139 ± 3.4

139 ± 3.6

140 ± 2.6

0.39

 Urea (mmol/L)

8.7 ± 3.8

8.8 ± 4.0

8.3 ± 3.5

0.46

 eGFR (ml/min per 1.73m2)

66 ± 19

66 ± 19

64 ± 19

0.46

 BNP (ng/L, median, IQR)

145 (66–259)

134 ± (57.5–251)

175 ± (111–263)

*0.12

CMR

 LVEF (%)

57 ± 6

57 ± 6

57 ± 7

0.98

 LVEDVI (ml/m2)

74 ± 18

73 ± 17

77 ± 21

0.26

 LVESVI (ml/m2)

33 ± 11

32 ± 10

34 ± 13

0.30

  1. Values are mean ± SD or n (%). The p values are for the t-test or chi-square test. ACEi angiotensin converting enzyme inhibitor; ARB = angiotensin II receptor blocker, BNP B-type natriuretic peptide, CMR cardiovascular magnetic resonance imaging, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, LVEDVI left ventricular end-diastolic volume indexed to body surface area, LVESVI left ventricular end-systolic volume indexed to body surface area; * p value refers to zlog10 transformed BNP