A comprehensive characterization of myocardial and vascular phenotype in pediatric chronic kidney disease using cardiovascular magnetic resonance imaging

Table 5 Cardiac timings and mitral inflow velocities in CKD

	Healthy Controls (n = 20)	Mild CKD (n = 40)	Moderate CKD (n = 40)	Severe CKD (n = 20)	P-value
IRT (ms)^a	61 ± 1.2	64 ± 1.1	70 ± 1.1	72 ± 1.1	< 0.001
ICT (ms)^a	44 ± 1.6	36 ± 1.6	33 ± 1.8	37 ± 1.8	0.24
ET (ms)	277 ± 21	275 ± 16	274 ± 19	276 ± 15	0.92
Tei^a	0.39 ± 1.3	0.37 ± 1.2	0.38 ± 1.2	0.41 ± 1.3	0.56
E (mls)	47 ± 9.8	49 ± 11	50 ± 11	49 ± 9.7	0.87
A (mls)	19 ± 4.3	20 ± 6.7	21 ± 6.8	22 ± 5.6	0.36
E/A ratio^a	2.6 ± 1.2	2.6 ± 1.4	2.5 ± 1.5	2.3 ± 1.3	0.63

Bonferroni correction applied- p < 0.007 is considered significant
Abbreviations: CKD chronic kidney disease, IRT isovolumic relaxation time, ICT isovolumic contraction time, ET ejection time, Tei myocardial performance index, E early transmitral mean velocity, A late transmitral mean velocity, E/A ratio E to A ratio
^aLogarithmic transformation was applied

ISSN: 1532-429X