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Table 4 Univariate and multivariate regression analysis for ECV and CVF in the patients awaiting heart transplantation

From: Association between myocardial extracellular volume and strain analysis through cardiovascular magnetic resonance with histological myocardial fibrosis in patients awaiting heart transplantation

  ECV CVF
  Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
Variables r value P value Standardised β P value r value P value Standardised β P value
Age (years) −0.032 0.888    0.174 0.439   
Sex (%) 0.425 0.049 0.250 0.007 0.196 0.381   
BMI (kg/m2) −0.130 0.563    −0.064 0.776   
Heart rate (bpm) −0.199 0.374    0.269 0.227   
Haematocrit (%) −0.400 0.065    −0.307 0.164   
Hypertension (%) −0.030 0.896    0.152 0.500   
Diabetes mellitus (%) −0.161 0.474    0.086 0.704   
Hyperlipidaemia (%) −0.114 0.612    −0.014 0.951   
Smoker (%) −0.370 0.090    −0.349 0.112   
Duration (years) −0.174 0.440    −0.094 0.678   
Time between CMR and transplantation (days) 0.562 0.006   0.507 0.451 0.035   0.581
NT-proBNP (pg/mL) 0.602 0.005   0.701 0.549 0.012   0.995
LV EF (%) −0.258 0.246    −0.126 0.576   
LV ESVI (mL/m2) −0.180 0.422    −0.316 0.153   
LV EDVI (mL/m2) −0.258 0.246    −0.262 0.240   
LV SVI (mL/m2) −0.325 0.140    −0.244 0.275   
LV cardiac index (L/min/m2) −0.359 0.101    −0.320 0.146   
LV mass index (g/m2) −0.400 0.065    −0.234 0.295   
LV GLS (%) 0.313 0.168    0.316 0.163   
LV GCS (%) 0.381 0.088    0.282 0.215   
LV GRS (%) −0.381 0.088    −0.290 0.202   
Native T1 time (ms)    0.508 0.016   0.138
ECV (%)    0.907 < 0.001 0.911 < 0.001
CVF (%) 0.907 < 0.001 0.860 < 0.001   
T2 mapping (ms) 0.339 0.143    0.258 0.272   
  1. CMR Cardiovascular magnetic resonance, BMI Body mass index, NT-proBNP N-terminal pro-brain natriuretic peptide, LV Left ventricle, EF Ejection fraction, ESVI End-systolic volume index, EDVI End-diastolic volume index, SVI Stroke volume index, GLS Global longitudinal strain, GCS Global circumferential strain, GRS Global radial strain, ECV Extracellular volume, CVF Collagen volume fraction