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Table 4 Univariate and multivariate regression analysis for ECV and CVF in the patients awaiting heart transplantation

From: Association between myocardial extracellular volume and strain analysis through cardiovascular magnetic resonance with histological myocardial fibrosis in patients awaiting heart transplantation

 

ECV

CVF

 

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

Variables

r value

P value

Standardised β

P value

r value

P value

Standardised β

P value

Age (years)

−0.032

0.888

  

0.174

0.439

  

Sex (%)

0.425

0.049

0.250

0.007

0.196

0.381

  

BMI (kg/m2)

−0.130

0.563

  

−0.064

0.776

  

Heart rate (bpm)

−0.199

0.374

  

0.269

0.227

  

Haematocrit (%)

−0.400

0.065

  

−0.307

0.164

  

Hypertension (%)

−0.030

0.896

  

0.152

0.500

  

Diabetes mellitus (%)

−0.161

0.474

  

0.086

0.704

  

Hyperlipidaemia (%)

−0.114

0.612

  

−0.014

0.951

  

Smoker (%)

−0.370

0.090

  

−0.349

0.112

  

Duration (years)

−0.174

0.440

  

−0.094

0.678

  

Time between CMR and transplantation (days)

0.562

0.006

 

0.507

0.451

0.035

 

0.581

NT-proBNP (pg/mL)

0.602

0.005

 

0.701

0.549

0.012

 

0.995

LV EF (%)

−0.258

0.246

  

−0.126

0.576

  

LV ESVI (mL/m2)

−0.180

0.422

  

−0.316

0.153

  

LV EDVI (mL/m2)

−0.258

0.246

  

−0.262

0.240

  

LV SVI (mL/m2)

−0.325

0.140

  

−0.244

0.275

  

LV cardiac index (L/min/m2)

−0.359

0.101

  

−0.320

0.146

  

LV mass index (g/m2)

−0.400

0.065

  

−0.234

0.295

  

LV GLS (%)

0.313

0.168

  

0.316

0.163

  

LV GCS (%)

0.381

0.088

  

0.282

0.215

  

LV GRS (%)

−0.381

0.088

  

−0.290

0.202

  

Native T1 time (ms)

  

0.508

0.016

 

0.138

ECV (%)

  

0.907

< 0.001

0.911

< 0.001

CVF (%)

0.907

< 0.001

0.860

< 0.001

  

T2 mapping (ms)

0.339

0.143

  

0.258

0.272

  
  1. CMR Cardiovascular magnetic resonance, BMI Body mass index, NT-proBNP N-terminal pro-brain natriuretic peptide, LV Left ventricle, EF Ejection fraction, ESVI End-systolic volume index, EDVI End-diastolic volume index, SVI Stroke volume index, GLS Global longitudinal strain, GCS Global circumferential strain, GRS Global radial strain, ECV Extracellular volume, CVF Collagen volume fraction