Parameters | All patients (n = 172) | Patients without the primary outcome (n = 129) | Patients with the primary outcome (n = 43) | P value |
---|---|---|---|---|
Age (years) | 56.4 ± 14.3 | 57.0 ± 14.6 | 54.8 ± 13.5 | 0.398 |
Male gender, n (%) | 116 (67.4) | 85 (65.9) | 31 (72.1) | 0.452 |
Mean arterial pressure (mmHg) | 84 ± 13 | 86 ± 13 | 80 ± 12 | 0.015 |
Hypertension, n (%) | 58 (33.7) | 44 (34.1) | 14 (32.6) | 0.852 |
Diabetes mellitus, n (%) | 36 (20.9) | 25 (19.4) | 11 (25.6) | 0.387 |
Dyslipidemia, n (%) | 11 (6.4) | 8 (6.2) | 3 (7.0) | 0.857 |
Current smoker, n (%) | 49 (28.5) | 37 (28.7) | 12 (27.9) | 0.734 |
Chronic kidney diseasea, n (%) | 31 (18.0) | 21 (16.3) | 10 (23.3) | 0.303 |
Previous CVA, n (%) | 4 (2.3) | 1 (0.8) | 3 (7.0) | 0.049 |
Body mass index (kg/m2) | 24.0 ± 4.5 | 24.2 ± 4.5 | 23.5 ± 4.4 | 0.347 |
ECG at baseline | Â | Â | Â | Â |
 Heart rate (bpm) | 83 ± 20 | 84 ± 19 | 83 ± 22 | 0.883 |
 Left bundle-branch block, n (%) | 31 (18.0) | 23 (17.8) | 8 (19.0) | 0.859 |
 QRS duration (ms) | 113 ± 29 | 112 ± 30 | 117 ± 29 | 0.305 |
Laboratory data | Â | Â | Â | Â |
 Serum creatinine (mg/dl) | 0.97 ± 0.27 | 0.96 ± 0.25 | 1.01 ± 0.31 | 0.247 |
 Na (mmol/l) | 139.6 ± 3.3 | 140.2 ± 2.8 | 137.6 ± 3.8 | < 0.001 |
 ln(NT-proBNP) (pg/ml) | 7.22 ± 1.27 | 7.08 ± 1.29 | 7.60 ± 1.16 | 0.022 |
Cardiac medications | Â | Â | Â | Â |
 Beta-blockers, n (%) | 120 (69.8) | 87 (67.4) | 33 (76.7) | 0.250 |
 ACE-inhibitors/ARB, n(%) | 134 (77.9) | 104 (80.6) | 39 (90.7) | 0.126 |
 Spironolactone, n (%) | 101 (58.7) | 74 (57.4) | 27 (62.8) | 0.531 |
 Diuretics, n (%) | 125 (72.7) | 93 (72.1) | 32 (74.4) | 0.767 |
 Digoxin, n (%) | 33 (19.2) | 21 (16.3) | 12 (27.9) | 0.094 |