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Table 1 Relation between circulating endothelial cell adhesion molecules (CAMs) and aortic characteristics

From: Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study

  Aortic wall area (cm2)b (n = 124) p value Aortic wall thickness (mm)b,d (n = 124) p value Aortic PWV (m/s)b,d (n = 118) p value
P-selectin (μg/ml)c
 Model 1 0.21 (0.04, 0.38) 0.02§ 0.19 (0.06, 0.32) 0.005§ −0.09 (− 0.32, 0.13) 0.41
 Model 2 0.14 (−0.02, 0.30) 0.08 0.18 (0.04, 0.31) 0.01§ −0.17 (− 0.39, 0.54) 0.14
E-selectin (μg/ml)c
 Model 1 0.01 (−2.26, 2.28) 0.99 0.26 (−1.46, 1.99) 0.77 3.83 (1.14, 6.53) 0.006§
 Model 2 −1.72 (−3.84, 0.39) 0.11 −0.45 (−2.28, 1.39) 0.63 3.01 (0.08, 5.95) 0.04§
ICAM − 1 (μg/ml)a,c
 Model 1 0.15 (−0.02, 0.32) 0.08 0.11 (−0.02, 0.24) 0.08 0.09 (−0.11, 0.30) 0.36
 Model 2 0.15 (−0.05, 0.26) 0.18 0.11 (−0.03, 0.24) 0.12 0.02 (−0.24, 0.27) 0.88
VCAM-1 (μg/ml)a,c
 Model 1 0.01 (−0.01, 0.03) 0.36 -1.59 × 10− 3 (− 0.02, 0.01) 0.85 − 0.01 (− 0.03, 0.01) 0.41
 Model 2 −2.03 × 10−3 (− 0.02, 0.02) 0.84 −2.73 × 10− 3 (− 0.02, 0.01) 0.75 −0.01 (− 0.03, 0.01) 0.53
  1. aPWV pulse wave velocity, ICAM-1 intercellular adhesion molecule, VCAM-1 vascular cell adhesion molecule
  2. bValues are linear mixed-effects regression coefficients (beta’s, (β)) with 95% confidence intervals
  3. cModel 1: crude model, Model 2: adjusted for age, sex, BMI, smoking, DBP, HDL-cholesterol and total cholesterol
  4. § p < 0.05
  5. dNatural logarithmic transformation was performed