Extracellular volume fraction measurements derived from the longitudinal relaxation of blood-based synthetic hematocrit may lead to clinical errors in 3 T cardiovascular magnetic resonance

Table 1 Patient characteristics for Derivation and Validation groups

	Derivation (n = 121)	Validation (n = 105)	P value
Age, years	49.8 ± 12.4	50.8 ± 13.0	0.554
Male, n (%)	66 (54.6)	65 (61.9)	0.264
BSA, m²	1.70 ± 0.22	1.72 ± 0.17	0.266
Healthy volunteer	18	27
Type 2 diabetes mellitus	34	26
Hypertrophic cardiomyopathy	49	44
Others	20	8
EDVi, ml/m²	71.0 ± 26.3	71.1 ± 25.6	0.968
ESVi, ml/m²	32.5 ± 26.5	30.8 ± 25.7	0.629
SVi, ml/m²	38.5 ± 8.8	40.3 ± 8.5	0.120
EF, %	56.9 ± 11.3	58.9 ± 10.0	0.174
CI, L/min/m²	2.82 ± 0.77	2.95 ± 0.62	0.159
LVMi, g/m²	80.8 ± 40.6	77.4 ± 34.3	0.506
Hematocrit, %	40.4 ± 4.7	40.9 ± 5.1	0.386
Myocardial native T1, ms	1285 ± 859	12,657 ± 75	0.055
Myocardial post-contrast T1, ms	504 ± 78	514 ± 54	0.273
Blood native T1, ms	1846 ± 120	1827 ± 130	0.242
Blood post-contrast T1, ms	343 ± 78	345 ± 54	0.883
ECV, %	30.3 ± 6.3	29.0 ± 4.2	0.059

BSA body surface area, EDVi end-diastolic volume index, ESVi end-systolic volume index, SVi stoke volume index, EF ejection fraction, CI cardiac index, LVMi left ventricular mass index, ECV extracellular volume

ISSN: 1532-429X