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Table 1 Characteristics of subjects

From: Diagnostic and prognostic significance of cardiovascular magnetic resonance native myocardial T1 mapping in patients with pulmonary hypertension

N Patients: PAH Group 3 PH LHD Patients: no PAH Healthy Subjects
369 39 82 24
Demographics and characteristics
 Age (years) 58.2 ± 15.0 68.1 ± 12.7** 55.4 ± 18.3 58.1 ± 3.88
 Sex (female %) 66.0 59.5 67.1 50.9
Subgroup diagnoses (n)   N/A N/A
Group 1 PAH n = 223    
PH-Lung n = 41    
 CTEPH n = 92    
 PH-MISC n = 10    
 BSA (m2) 1.81 ± 250 1.89 ± 0.26 1.85 ± 0.25  
CMR
 Heart Rate (bpm) 72.17 ± 14.4 69.81 ± 3.8 67.9 ± 10.3**  
 CMR at incident vs prevalent time (incident %) N = 165 (45%) N = 31 (80%) N = 82 (100%)  
 RV insertion T1 (ms) 1065 ± 86 1074 ± 10 1017 ± 69 943 ± 52**
 Septal T1 (ms) 975 ± 67 986 ± 73 976 ± 75 940 ± 56*
 LV free wall T1 (ms) 965 ± 68 982 ± 81 961 ± 66 913 ± 55**
 RVEDV Index (ml/m2) 87.2 ± 34.1 81.9 ± 31.7 68.0 ± 20.4**  
 RVESV Index (ml/m2) 51.7 ± 29.0 45.4 ± 23.1 31.1 ± 11.6**  
 RVSV Index (%) 35.6 ± 14.2 36.5 ± 12.1 36.9 ± 12.9  
 RVEF (%) 43.1 ± 13.6 46.8 ± 11.2 54.4 ± 10.0**  
 LVEDV Index (ml/m2 58.5 ± 16.1 68.9 ± 21.2** 66.6 ± 16.1**  
 LVESV Index ml/m2) 19.2 ± 8.2 26.1 ± 16.6** 21.3 ± 8.2*  
 LVSV Index (%) 39.2 ± 11.9 42.8 ± 13.4 45.3 ± 10.8**  
 LVEF (%) 67.3 ± 9.7 63.8 ± 14.5 68.3 ± 7.6  
 Systolic septal angle (°) 165.5 ± 23.9 145.9 ± 15.5 150.5 ± 108.4*  
 Diastolic septal angle (°) 143.34 ± 11.0 138.3 ± 10.3** 134.9 ± 7.9*  
 RV mass index (g/m2) 21.9 ± 12.5 14.4 ± 5.5** 11.9 ± 5.8*  
 LV mass index (g/m2) 48.0 ± 12.3 57.2 ± 21.1** 47.7 ± 10.7  
 VMI (ratio) 0.47 ± 0.27 0.28 ± 0.13** 0.26 ± 0.18*  
  1. WHO world health organisation, PAH ipulmonary arterial hypertension, CTEPH chronic thromboembolic pulmonary hypertension, RVEDV right ventricular end diastolic volume, RVESV right ventricular end systolic volume, RVSV right ventricular stroke volume, RVEF right ventricular ejection fraction, VMI ventricular mass index, LVEDV left ventricular end diastolic volume, LVESV left ventricular end systolic volume, LVSV left ventricular stroke volume, LVEF left ventricular ejection fraction, VMI ventricular mass index, CMR cardiovascular magnetic resonance
  2. P values indicate comparisons between patients with PH and the other two groups. * signifies a p value < 0.05, ** signifies a p value < 0.025