Fig. 1

A 22-year-old man, who was transplanted for a non-malignant bone marrow failure disorder at the age of 8 years. a the transmitral E/A ratio (early peak filling rate/late peak filling rate) was measured using 2D velocity-encoded CMR (left panel) and Ea (early peak diastolic mitral septal tissue velocity) was derived from the four-chamber long-axis relaxation (right panel). LV filling pressure was estimated by the ratio of the transmitral early peak maximum velocity and the early peak diastolic mitral septal tissue velocity. b From two, three- and four-chamber and mid-ventricular short-axis cine CMR (left panel), the longitudinal and circumferential strain and strain rate curves were extracted (right panel). The myocardial features at the endocardial borders (red dots), which were automatically tracked throughout the cardiac cycle (green lines), were manually annotated in the end-diastolic and end-systolic phase. GLS: global longitudinal strain; GCS: global circumferential strain; GLSR-S: global longitudinal peak systolic strain rate; GCSR-E: global circumferential early peak diastolic strain rate