Table 1 Demographic, clinical and electrocardiographic findings in the study cohort
Whole Cohort (N = 52) | Conduction Abnormality Positive (N = 31) | Conduction Abnormality Negative (N = 21) | P value | |
|---|---|---|---|---|
Demographic data | ||||
Age, years | 41.2 ± 13.9 | 43.7 ± 11.9 | 37.4 ± 15.9 | 0.129 |
Male gender, N (%) | 20 (38) | 11 (35) | 9 (43) | 0.772 |
BMI, kg/m2 | 25.5 ± 5.8 | 25.8 ± 6.2 | 24.9 ± 5.1 | 0.618 |
DM, N (%) | 5 (10) | 4 (13) | 1 (5) | 0.637 |
HTN, N (%) | 3 (6) | 1 (3) | 2 (9) | 0.558 |
Smoking, N (%) | 2 (4) | 2 (6) | 0 (0) | 0.494 |
HLP, N (%) | 5 (10) | 4 (13) | 1 (5) | 0.637 |
History of CAD, N (%) | 1 (2) | 1 (3) | 0 (0) | 0.999 |
BB, N (%) | 4 (8) | 3 (10) | 1 (5) | 0.639 |
ACE-i, N (%) | 3 (6) | 2 (6) | 1 (5) | 0.999 |
ARB, N (%) | 1 (2) | 1 (3) | 0 (0) | 0.999 |
MCRA, N (%) | 4 (8) | 4 (13) | 0 (0) | 0.138 |
Statin, N (%) | 6 (11) | 4 (13) | 2 (9) | 0.999 |
Myotonic Muscular Dystrophy Characteristics | ||||
Age of onset, years | 28.8 ± 15.5 | 28.2 ± 17.1 | 29.6 ± 13.1 | 0.749 |
Disease length, years | 12.4 ± 12.7 | 15.5 ± 14.8 | 7.8 ± 6.9 | 0.015* |
CTG Repeats | 500 (200–1163) | 280 (142–772) | 575 (450–1450) | 0.137 |
MIRS scale | 3 (3–4) | 3 (3–4) | 3 (2–3) | 0.041* |
Clinical data | ||||
SBP, mmHg | 126 ± 18 | 125 ± 18 | 126 ± 19 | 0.798 |
DBP, mmHg | 74 ± 10 | 74 ± 11 | 75 ± 8 | 0.733 |
HR, bpm | 74 ± 14 | 74 ± 16 | 75 ± 12 | 0.793 |
NYHA class | 2 (1–2) | 2 (1–2) | 1 (1–2) | 0.900 |
Hematocrit, % | 42.1 ± 3.8 | 42.3 ± 3.4 | 41.7 ± 4.4 | 0.592 |
Electrocardiographic Data | ||||
PR, ms | 199 ± 47 | 223 ± 48 | 165 ± 16 | < 0.001 |
QRS, ms | 103 ± 20 | 111 ± 22 | 94 ± 11 | 0.001 |
QT, ms | 404 ± 42 | 412 ± 47 | 392 ± 31 | 0.070 |
QTc, ms | 428 ± 32 | 431 ± 38 | 423 ± 23 | 0.359 |
Frontal QRS-T angle | 41 ± 41 | 45 ± 44 | 36 ± 36 | 0.447 |
LVH-Cornell, N (%) | 13 (25) | 11 (35) | 2 (9) | 0.050 |