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Table 2 Cardiovascular magnetic resonance findings

From: Loss of base-to-apex circumferential strain gradient assessed by cardiovascular magnetic resonance in Fabry disease: relationship to T1 mapping, late gadolinium enhancement and hypertrophy

 

Healthy Controls (n = 8)

Fabry Disease Patients (n = 38)

p-value

LVEDV (mL)

178.5 ± 46.4

154.6 ± 34.9

0.16

LVEDVi (mL/m2)

96.3 ± 13.9

84.2 ± 20.2

0.043

LVESV (mL)

73.1 ± 23.8

63.2 ± 18.1

0.23

LVESVi (mL/m2)

39.3 ± 8.7

34.4 ± 10.3

0.10

LVSV (mL)

105.4 ± 23.3

91.4 ± 20.0

0.09

LVEF (%)

59.6 ± 3.6

59.31 ± 4.6

0.86

Cardiac output (L/min)

6.3 ± 1.5

6.2 ± 1.2

0.86

LV mass (g)

99.9 ± 37.1

131.2 ± 57.8

0.22

LVMi (g/m2)

53.4 ± 15.7

71.0 ± 31.5

0.21

LGE (presence)

0.0 (0%)

17 (45%)

0.019

LGE (%)

0.0 ± 0.0

2.0 ± 3.5

< 0.001

Native T1 (ms)

1239.0 ± 18.0

1170.2 ± 37.5

< 0.001

ECV (%)

25.9 ± 3.2

25.6 ± 2.9

0.48

GLS (%)

-16.3 ± 1.5

−15.3 ± 3.5

0.45

GCS (%)

−19.5 ± 2.9

−19.4 ± 3.0

0.84

Base-to-apex LS gradient (%)

9.3 ± 3.5

7.5 ± 3.8

0.24

Base-to-apex CS gradient (%)

6.5 ± 2.2

2.1 ± 3.7

0.002

  1. Comparisons between groups were made by independent samples t-test, Wilcoxon rank sum test or Fisher’s exact test. Continuous variables are presented as mean ± SD. Categorical variables are presented as number of subjects with percentage in parentheses. CS circumferential strain, ECV extracellular volume, FD Fabry disease, GCS global circumferential strain, GLS global longitudinal strain, LGE late gadolinium enhancement, LS longitudinal strain, LV Left ventricle, LVMi left ventricular mass indexed to body surface area (BSA), LVEF left ventricular ejection fraction, LVEDV left ventricular end diastolic volume, LVEDVi LVEDV indexed to BSA, LVESV left ventricular end systolic volume, LVESVi LVESV indexed to BSA, LVSV left ventricular stroke volume
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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