Fig. 1

Representative mean diffusivity (MD), fractional anisotropy (FA) and native T1 maps for a healthy control (a) and a light chain (AL) amyloidosis patient (b). Enhanced T1 mapping, extracellular volume fraction (ECV) mapping and late gadolinium enhancement (LGE) CMR imaging was only performed in the cardiac amyloid (CA) patient. It can be appreciated, that the areas of signal hyperenhancement in LGE and elevated ECV correspond well with regions of high MD and low FA in the parameter maps derived from CMR diffusion tensor imaging (DTI) in the CA patient