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Table 2 Univariate analysis of all patients (n = 74) for primary endpoint (death)

From: Prognostic value of novel imaging parameters derived from standard cardiovascular magnetic resonance in high risk patients with systemic light chain amyloidosis

 

Primary endpoint

 

Variable

Hazard ratio

95% CI

p-value

NYHA class

1.8

1.1–2.9

0.02

Karnofsky Index

0.94

0.92–0.97

<  0.001

dFLC (mg/dL)

1.0

0.99–1.01

0.27

Positive Troponin values

2.3

1.2–4.7

0.02

ln NT-pro BNP

2.8

0.98–8.1

0.06

LAS (%)

1.2

1.1–1.4

<  0.001

MCF (%)

0.96

0.94–0.98

< 0.001

LVESVI (ml/m2)

1.01

0.99–1.04

0.13

LVEF (%)

0.97

0.94–0.99

0.02

LVMI (g/m2)

1.02

1.01–1.03

< 0.001

GLS (%)

0.92

0.85–0.99

0.04

  1. Abbreviations: dFLC free light chain difference, GLS global longitudinal strain, LAS long axis strain, LVESVI left ventricular end-systolic volume index, LVEF left ventricular ejection fraction, LVMI left ventricular mass index, MCF myocardial contraction fraction, NYHA New-York-Heart-Association, NT-pro BNP N-terminale natriuretic peptide
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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