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Table 3 Univariate analysis of all patients (n = 74) for composite endpoint (death and heart transplantation)

From: Prognostic value of novel imaging parameters derived from standard cardiovascular magnetic resonance in high risk patients with systemic light chain amyloidosis

 

Composite endpoint

 

Variable

Hazard ratio

95% CI

p-value

NYHA class.

1.9

1.2–3.0

0.006

Karnofsky Index

0.95

0.93–0.98

< 0.001

dFLC (mg/dL)

1.0

0.99–1.01

0.2

Positive Troponin values

2.5

1.3–4.6

0.005

ln NT-pro BNP

3.8

1.3–11

0.01

LAS (%)

1.23

1.1–1.4

< 0.001

MCF (%)

0.96

0.94–0.99

< 0.001

LVESVI (ml/m2)

1.04

1.02–1.04

0.006

LVEF (%)

0.95

0.92–0.97

< 0.001

LVMI (g/m2)

1.01

1.0–1.03

< 0.001

GLS (%)

0.91

0.85–0.97

0.005

  1. Abbreviations: dFLC free light chain difference, GLS global longitudinal strain, LAS long axis strain, LVEDVI left ventricular end-diastolic volume index, LVESVI left ventricular end-systolic volume index, LVEF left ventricular ejection fraction, LV MI left ventricular mass index, MCF myocardial contraction fraction, NYHA New-York-Heart-Association, NT – pro BNP N-terminale natriuretic peptide
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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