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Table 4 Cox regression hazard models of risk factors for vascular events

From: Co-existing cerebrovascular atherosclerosis predicts subsequent vascular event: a multi-contrast cardiovascular magnetic resonance imaging study

 

Vascular events

Univariate Regression

Multivariate Regression*

HR

95% CI

P value

HR

95% CI

P value

Extracranial carotid artery

 Maximum wall thickness, mm

1.06

0.88–1.28

0.542

0.91

0.67–1.23

0.526

 Presence of calcification

1.40

0.76–2.60

0.280

1.04

0.32–3.33

0.954

 Presence of LRNC

3.65

1.60–8.35

0.002

4.26

0.96–18.80

0.056

 Presence of IPH

1.25

0.60–2.64

0.552

0.57

0.09–3.60

0.552

 Presence of stenosis

1.16

0.62–2.16

0.647

–

–

–

Intracranial artery

 Presence of stenosis

2.73

1.25–5.97

0.012

5.95

0.97–36.38

0.054

Co-existing plaques

 Intracranial stenosis and extracranial carotid plaque

3.57

1.63–7.82

0.001

5.12

1.36–19.24

0.016

 Intracranial stenosis and extracranial carotid calcification

1.74

0.94–3.24

0.078

2.95

0.76–11.42

0.117

 Intracranial stenosis and extracranial carotid LRNC

4.47

2.15–9.27

< 0.001

8.12

2.41–27.31

0.001

 Intracranial stenosis and extracranial carotid IPH

1.67

0.77–3.63

0.194

1.44

0.17–12.39

0.738

  1. HR hazard ratio, CI confidence interval, LRNC lipid-rich necrotic core, IPH intraplaque hemorrhage. *Adjusted for baseline confounding factors including age, sex, BMI, history of stroke, diabetes, hypertension, hyperlipidemia, coronary heart disease, smoking, NIHSS score, and carotid stenosis and treatment procedures during follow-up including antihypertension treatment, lipid-lowering treatment, anticoagulation treatment and antiplatelet treatment
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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