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Table 2 Baseline characteristics according to mvPA

From: Prognostic value of mean velocity at the pulmonary artery estimated by cardiovascular magnetic resonance as a prognostic predictor in a cohort of patients with new-onset heart failure with reduced ejection fraction

 

mvPA > 9 cm/s

n = 115

mvPA ≤9 cm/s

n = 95

Total

n = 210

p value

Echocardiography

LVEF (%)

28.9 ± 9.8

26.4 ± 9.0

27.8 ± 9.6

0.056

LVEDD (mm)

58.7 ± 7.7

60.1 ± 7.2

59.3 ± 7.5

0.288

LVESD (mm)

46.8 ± 9.2

48.7 ± 8.9

47.6 ± 9.1

0.238

RV diameter (mm)

22.3 ± 5.3

25.4 ± 7.8

23.9 ± 6.9

0.010

TAPSE (mm)

17.8 ± 5.1

16.0 ± 4.2

48.1 ± 14.5

0.044

SPAP (mmHg)a

46.8 ± 16.2

49.4 ± 12.7

16.9 ± 4.7

0.321

TAPSE/sPAP ratio (mm/mmHg)a

0.45 ± 0.27

0.34 ± 0.15

0.39 ± 0.22

0.020

CMR

LVEF (%)

28.8 ± 10.4

24.4 ± 9.0

26.9 ± 10.0

0.001

LVEDVI (mL/m2)

124.3 ± 41.0

136.2 ± 45.2

129.7 ± 43.2

0.047

LVESVI (mL/m2)

91.1 ± 40.2

103.5 ± 43.0

96.7 ± 41.8

0.033

RVEF (%)

46.1 ± 14.6

39.4 ± 16.2

43.1 ± 15.7

0.002

RVEDVI (mL/m2)

71.2 ± 27.8

84.1 ± 36.2

77.1 ± 32.5

0.004

RVESVI (mL/m2)

39.3 ± 21.4

53.9 ± 32.5

45.9 ± 27.9

<  0.001

LGE ischemic-pattern(n,%)

28(29.8%)

27(36%)

55(32.5%)

0.392

LGE non-ischemic pattern(n,%)

33(35.5%)

35(47.3%)

68(40.7%)

0.123

mvPA (cm/s)

12.7 ± 3.4

7.0 ± 1.6

10.1 ± 3.9

<  0.001

PVR (WU)

3.9 ± 1.7

7.3 ± 1.8

5.5 ± 2.4

<  0.001

RV-PA unit parameters

Maximal PA-area (cm2)

7.9 ± 2.0

9.3 ± 2.5

8.6 ± 2.4

<  0.001

Minimal PA-are a (cm2)

5.9 ± 1.8

7.3 ± 1.8

6.6 ± 2.1

<  0.001

PA pulsatility(%)

0.35 ± 0.19

0.30 ± 0.15

0.33 ± 0.18

0.068

RV Emax/Ea

1.03 ± 0.66

0.76 ± 0.52

0.91 ± 0.61

0.002

Right heart catheterisation parameters

 

mvPA > 9 cm/s

n = 27

mvPA ≤ 9 cm/s

n = 28

Total

n = 55

p value

mPAP (mmHg)

29.4 ± 11.7

33.4 ± 8.9

31.4 ± 10.5

0.162

PCWP (mmHg)

20.6 ± 8.2

21.1 ± 7.7

20.8 ± 7.8

0.808

RA Pressure (mmHg)

11.1 ± 6.9

13.4 ± 5.9

12.3 ± 6.4

0.243

Cardiac output (l/min)

4.1 ± 1.6

3.2 ± 1.1

3.6 ± 1.4

0.063

PVR (WU)

2.8 ± 2.4

4.1 ± 2.3

3.4 ± 2.4

0.096

TPG (mmHg)

8.5 ± 6.9

12.6 ± 7.4

10.6 ± 7.4

0.042

Pulse Pressure (mmHg)

21.0 ± 9.5

29.6 ± 13.2

25.4 ± 12.9

0.012

PA Compliance (mm3/mmHg)

2.02 ± 0.94

1.39 ± 0.79

1.67 ± 0.90

0.022

  1. a Measures available for 139 patients
  2. CMR cardiovascular magnetic resonance. Ea effective elastance. Emax right ventricular maximal end-systolic elastance. LVEDVI left ventricular end-diastolic volume index. LVESV left ventricular end-systolic volume index. RVEDV right ventricular end-diastolic volume index. RVESV right ventricular end-systolic volume index. LGE late gadolinium enhancement. LVEF left ventricular ejection fraction. LVEDD left ventricular end-diastolic diameter. LVESD left ventricular end-systolic diameter. MPAP mean pulmonary artery pressure. mvPA mean velocity at the pulmonary artery. PA pulmonary artery. PCWP pulmonary capillary wedge pressure. PVR pulmonary vascular resistance. RA right atrium. RV right ventricle. RVEF right ventricular ejection fraction. sPAP systolic pulmonary artery pressure. TAPSE tricuspid annular plane excursion. TPG transpulmonary gradient. WU wood units