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Table 1 The effect of early intravenous metoprolol on infarct and remote zone strain

From: Left ventricular functional recovery of infarcted and remote myocardium after ST-segment elevation myocardial infarction (METOCARD-CNIC randomized clinical trial substudy)

 

Infarct zone circumferential strain (%)

Remote zone circumferential strain (%)

1 week

6 months

MD [95% CI]

P-value*

1 week

6 months

MD [95% CI]

P-value*

Metoprolol (N = 97)

−9.9 ± 7.6

− 15.7 ± 7.5

−5.7 [− 6.8 to − 4.6]

< 0.001

−19.7 ± 3.6

− 19.2 ± 4.1

0.6 [− 0.2 to 1.3]

0.153

Control (N = 94)

−7.2 ± 10.1

−13.2 ± 8.3

−6.0 [− 7.7 to − 4.2]

< 0.001

− 19.3 ± 7.5

− 19.3 ± 3.7

0.0 [− 1.4 to 1.4]

0.984

MD [95% CI]

−2.7 [− 5.3 to − 0.1]

−2.5 [− 4.7 to − 0.2]

  

−0.5 [− 2.1 to 1.2]

0.1 [− 1.0 to 1.2]

  

P-value

0.038

0.033

  

0.589

0.876

  
  1. CI confidence interval, MD mean difference
  2. *the P-values for the strain difference between 6 months and 1 week
  3. †the P-values for the strain difference between the group