Table 1 Baseline characteristics of surgical patients according to symptom status
N | Asymptomatic N = 65 | Symptomatic N = 39 | P-value | |
|---|---|---|---|---|
Clinical characteristics | ||||
Age (years) | 104 | 62 ± 14 | 64 ± 12 | 0.428 |
Male sex | 104 | 50 (77%) | 26 (67%) | 0.254 |
BMI (kg/m2) | 104 | 25 ± 4 | 27 ± 5 | 0.065 |
BSA (m2) | 104 | 1.88 ± 0.23 | 1.91 ± 0.23 | 0.491 |
Treated hypertension | 104 | 20 (31%) | 12 (31%) | 1.000 |
Atrial fibrillation | 104 | 0.008 | ||
None | 53 (82%) | 21 (54%) | ||
Paroxysmal | 2 (3%) | 5 (13%) | ||
Permanent | 10 (15%) | 13 (33%) | ||
eGFR (ml/min/1.73m2) | 104 | 75 (65–84) | 72 (60–82) | 0.401 |
Degeneration subtype | 104 | 0.076 | ||
Barlow’s disease | 24 (37%) | 11 (28%) | ||
Indeterminant | 3 (5%) | 7 (18%) | ||
Fibroelastic deficiency | 38 (58%) | 21 (54%) | ||
MLHFQ score | 103 | 5 (1–17) | 43 (30–57) | < 0.001 |
%PredVO2max (%) | 103 | 99 ± 20 | 79 ± 22 | < 0.001 |
Resting PASP (mmHg) | 85 | 33 ± 10 | 38 ± 20 | 0.071 |
Ventricular ectopy burden (%) | 54 | 0.1 (0.0–1.0) | 0.5 (0.0–1.4) | 0.356 |
Cardiac magnetic resonance characteristics | ||||
LVEDVI (ml/m2) | 104 | 105 ± 22 | 103 ± 21 | 0.663 |
LVESVI (ml/m2) | 104 | 33 ± 13 | 35 ± 11 | 0.342 |
LVESD (mm) | 104 | 3.7 ± 0.7 | 3.8 ± 0.6 | 0.380 |
LVMI (g/m2) | 104 | 71 ± 13 | 66 ± 13 | 0.045 |
LVEF (%) | 104 | 70 ± 8 | 66 ± 9 | 0.065 |
GCS (%) | 102 | − 18.2 ± 3.0 | − 16.6 ± 3.5 | 0.017 |
GLS (%) | 102 | − 15.9 ± 2.7 | − 14.8 ± 3.3 | 0.099 |
LAVI (ml/m2) | 102 | 88 ± 44 | 96 ± 47 | 0.341 |
RVESVI (ml/m2) | 104 | 31 ± 9 | 33 ± 13 | 0.474 |
RVEF (%) | 104 | 57 ± 8 | 55 ± 10 | 0.122 |
RV Ell | 104 | − 21.6 ± 4.5 | − 21.4 ± 5.0 | 0.811 |
MR volume (ml) | 104 | 62 ± 27 | 67 ± 36 | 0.410 |
MR fraction (%) | 104 | 44 ± 12 | 49 ± 19 | 0.121 |
ECV (%) | 101 | 26.8 ± 3.1 | 28.2 ± 3.3 | 0.045 |
Native T1 (ms) | 103 | 981 ± 24 | 991 ± 26 | 0.054 |
LGE presence (n, %) | 102 | 22 (34%) | 12 (32%) | 0.830 |
LGE quantification (g) | 102 | 0.00 (0.00–0.37) | 0.00 (0.00–0.24) | 0.452 |