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Table 28 References, normal thickness, mass, ratios and fractal dimension of the left ventricular trabeculated (non-compacted) myocardium in the adult

From: Reference ranges (“normal values”) for cardiovascular magnetic resonance (CMR) in adults and children: 2020 update

First author, year

CMR technique

n, male:female

Age range (years)

Trabeculation thickness (thickness of the trabeculated [non-compacted] LV myocardium)

Dawson, 2011 [56]

1.5 T, short axis bSSFP, maximal thickness per segment at diastole and systole

60:60

20–80

NC/C thickness ratio (thickness of trabeculated [non-compacted] LV myocardium/ thickness of compact LV myocardium)

Dawson, 2011 [56]

1.5 T, short axis bSSFP, NC/C thickness ratio per segment measured manually at the “peak of the most prominent trabeculae in each segment” at diastole and systole

60:60

20–80

Kawel, 2012 [61]

1.5 T, long axis bSSFP at diastole, maximal NC/C thickness ratio of 12 segments

192:175

54–91

Captur, 2013 [59]

1.5 T, long axis bSSFP at diastole, maximal NC/C thickness ratio of 16 segments

40 (total)*

18–85

Tizón-Marcos, 2014 [65]

1.5 T, long- and short axis bSSFP, mean NC/C thickness ratio per segment measured semi-automatically by the centerline method (average of 20–30 chords/segment) at diastole and systole

45:55

18–35

Amzulescu, 2015 [58]

1.5 T and 3 T, long axis bSSFP at diastole, maximal NC/C thickness ratio of 16 segments

22:26

(60 ± 10)**

André, 2015 [64]

1.5T, long axis bSSFP at diastole, maximal NC/C thickness ratio of 16 segments

58:59

20– > 50

Trabeculation mass (mass of the trabeculated [non-compacted] LV myocardium)

Bentatou, 2018 [12]

1.5 T, short axis bSSFP at diastole, papillary muscles and blood between trabeculae excluded

70:70

20–69

Trabeculation volume (volume of the trabeculated [non-compacted] LV myocardium)

André, 2015 [64]

1.5 T, short axis bSSFP, blood between trabeculae included, papillary muscles excluded

58:59

20– > 50

NC/C mass ratio (mass of trabeculated [non-compacted] LV myocardium/ mass of compact LV myocardium)

Amzulescu, 2015 [58]

1.5 T and 3 T, short axis bSSFP at diastole, mass of trabeculated myocardium includes trabeculae and blood between trabeculae, papillary muscles excluded from trabeculated and compact mass

22:26

(60 ± 10)b

Bentatou, 2018 [12]

1.5 T, short axis bSSFP at diastole, blood between trabeculae excluded from mass of trabeculated myocardium, papillary muscles included in mass of compact myocardium

70:70

20–69

NC/TM (mass of trabeculated [non-compacted] LV myocardium/ total LV myocardial mass [trabeculated + compact LV myocardial mass])

Captur, 2013 [59]

1.5 T, short axis bSSFP at diastole, mass of trabeculated myocardium includes trabeculae and blood between trabeculae, papillary muscles included in mass of compact myocardium

40 (total)a

18–85

Fractal dimension (fractal complexity of LV trabeculated [non-compacted] myocardium)

Captur, 2013 [59]

1.5 T, short axis bSSFP at diastole, papillary muscles included in the endocardial complexity

51:54 (75 white, 30 black)

18–85

Captur 2015 [62]

1.5 T, short axis bSSFP at diastole, papillary muscles included in the endocardial complexity

279:325

46–91

Cai, 2017 [66]

3 T, short axis bSSFP at diastole, papillary muscles included in the endocardial complexity

91:89

20–69

  1. n number of study subjects, LV left ventricular, bSSFP balanced steady-state free precession
  2. aMale:female ratio not provided in original publication
  3. bAge range not provided in original publication