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Table 1 Patient characteristics in the subgroups with or without cardiac amyloidosis (CA)

From: Deep learning to diagnose cardiac amyloidosis from cardiovascular magnetic resonance

 

All

n = 206

CA

n = 107 (52%)

No CA

n = 99 (48%)

*p-value

Age (years)

76 (69–81)

76 (69–81)

73 (65–79)

0.178

Male sex (n, %)

137 (67)

79 (74)

58 (59)

0.021

BSA (m2)

1.84 (1.74–1.96)

1.84 (1.72–1.94)

1.85 (1.75–2.01)

0.399

CMR findings

 LVEDVI (mL/m2)

79 (67–96)

79 (67–92)

81 (67–97)

0.153

 LVESVI (mL/m2)

33 (23–50)

31 (24–46)

36 (22–56)

0.445

 LVSVI (mL/m2)

44 (37–51)

43 (36–51)

45 (39–51)

0.192

 LVEF (%)

55 (46–67)

57 (46–65)

55 (44–67)

0.625

 CO (L/min)

5.3 (4.3–6.6)

5.3 (4.3–6.5)

5.2 (4.4–6.7)

0.752

 LVMI (g/m2)

84 (71–111)

95 (77–118)

73 (64–98)

 < 0.001

 LA area index (cm2/m2)

16 (13–18)

17 (14–18)

14 (12–18)

0.008

 RA area index (cm2/m2)

13 (11–15)

14 (12–16)

12 (10–14)

 < 0.001

 RVEDVI (mL/m2)

70 (57–81)

74 (60–83)

63 (55–77)

0.013

 RVESVI (mL/m2)

28 (20–37)

32 (22–41)

24 (18–32)

 < 0.001

 RVSVI (mL/m2)

39 (33–47)

38 (32–43)

41 (36–49)

0.087

 RVEF (%)

59 (47–65)

54 (44–63)

61 (57–68)

 < 0.001

Early bloodpool darkening (n, %)

40 (19)

39 (36)

1 (1)

 < 0.001

LGE presence (n, %)

174 (84)

105 (98)

69 (69)

 < 0.001

LGE subendocardial-to-transmural pattern (n, %)

89 (43)

85 (79)

4 (4)

 < 0.001

Pericardial effusion (n, %)

48 (23)

30 (28)

18 (18)

0.087

Pleural effusion (n, %)

58 (28)

45 (42)

13 (13)

 < 0.001

  1. AL amyloid light-chain, ATTR amyloid transthyretin, BSA body surface area, CMR cardiovascular magnetic resonance, CO cardiac output, LA left atrium, LGE late gadolinium enhancement, LVEDVI left ventricular end-diastolic volume index, LVESVI left ventricular end-systolic volume index, LVEF left ventricular ejection fraction, LVMI left ventricular mass index, LVSVi left ventricular stroke volume index, RA right atrium, RVEDVI right ventricular end-diastolic volume index, RVESVI right ventricular end-systolic volume index, RVEF right ventricular ejection fraction, RVSVI right ventricular stroke volume index
  2. *p-values represent the difference between patients with CA and without CA (no CA), p-values less than 0.05 are shown in italic