Table 2 CMR Diagnostic Criteria for LVNC
| Â | All patients and healthy subjects | Subgroup A | Subgroup B | Subgroup C | Subgroup D | A vs. B | A vs. C | A vs. D | C vs. D | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
All LVNC phenotype patients | All healthy subjects | p-values | LVNC phenotype patients (normal LV volumetrics) | Healthy subjects (normal LV volumetrics) | Healthy subjects (normal LV volumetrics, not meeting any LVNC criteria) | Healthy subjects (normal LV volumetrics, meeting one or more LVNC criteria) | p-values | p-values | p-values | p-values | |
(n = 59) | (n = 36) |  | (n = 25) | (n = 34) | (n = 16) | (n = 18) |  |  |  |  | |
Number of NC segmentsb | 8 (6, 9) | 0 (0, 0) | < 0.001 | 8 (6, 9) | 0 (0, 0) | 0 (0, 0) | 0 (0, 1) | < 0.001 | < 0.001 | < 0.001 | 0.013 |
Maximum NC:C ratiob | 3.8 (3.0, 4.3) | 1.2 (0.9, 1.6) | < 0.001 | 3.5 (3.2, 4.3) | 1.1 (0.9, 1.3) | 1.0 (0.8, 1.2) | 1.2 (0.9, 2.5) | < 0.001 | < 0.001 | < 0.001 | 0.182 |
NC:C > 2.3a | 59 (100%) | 7 (19.4%) | < 0.001 | 25 (100%) | 6 (17.7%) | 0 (0%) | 6 (33.3%) | < 0.001 | < 0.001 | < 0.001 | 0.020 |
Percentage of NC mass (%)b | 40.8 (35.7, 45.9) | 19.5 (17.2, 23.3) | < 0.001 | 42.2 (38.7, 47.1) | 19.3 (17.1, 23.6) | 17.2 (14.8, 18.5) | 23.3 (20.1, 30.7) | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
NC mass > 20%a | 59 (100%) | 16 (44.4%) | < 0.001 | 25 (100%) | 14 (41.2%) | 0 (0%) | 14 (77.8%) | < 0.001 | < 0.001 | 0.025 | < 0.001 |
NC mass > 25%a | 59 (100%) | 5 (13.9%) | < 0.001 | 25 (100%) | 5 (14.7%) | 0 (0%) | 5 (27.8%) | < 0.001 | < 0.001 | < 0.001 | 0.046 |
NC mass/BSA (g/m2)b | 36.1 (32.3, 42.9) | 13.6 (10.5, 17.2) | < 0.001 | 35.1 (30.9, 39.2) | 12.7 (10.4, 17.0) | 10.0 (8.8, 11.6) | 17.0 (15.0, 23.7) | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
NC mass > 15 g/m2a | 59 (100%) | 15 (41.7%) | < 0.001 | 25 (100%) | 13 (38.2%) | 0 (0%) | 13 (72.2%) | < 0.001 | < 0.001 | 0.009 | < 0.001 |