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Table 2 CMR Diagnostic Criteria for LVNC

From: Cardiovascular magnetic resonance based diagnosis of left ventricular non-compaction cardiomyopathy: impact of cine bSSFP strain analysis

 All patients and healthy subjectsSubgroup ASubgroup BSubgroup CSubgroup DA vs. BA vs. CA vs. DC vs. D
All LVNC phenotype patientsAll healthy subjectsp-valuesLVNC phenotype patients (normal LV volumetrics)Healthy subjects (normal LV volumetrics)Healthy subjects (normal LV volumetrics, not meeting any LVNC criteria)Healthy subjects (normal LV volumetrics, meeting one or more LVNC criteria)p-valuesp-valuesp-valuesp-values
(n = 59)(n = 36) (n = 25)(n = 34)(n = 16)(n = 18)    
Number of NC segmentsb8 (6, 9)0 (0, 0)< 0.0018 (6, 9)0 (0, 0)0 (0, 0)0 (0, 1)< 0.001< 0.001< 0.0010.013
Maximum NC:C ratiob3.8 (3.0, 4.3)1.2 (0.9, 1.6)< 0.0013.5 (3.2, 4.3)1.1 (0.9, 1.3)1.0 (0.8, 1.2)1.2 (0.9, 2.5)< 0.001< 0.001< 0.0010.182
NC:C > 2.3a59 (100%)7 (19.4%)< 0.00125 (100%)6 (17.7%)0 (0%)6 (33.3%)< 0.001< 0.001< 0.0010.020
Percentage of NC mass (%)b40.8 (35.7, 45.9)19.5 (17.2, 23.3)< 0.00142.2 (38.7, 47.1)19.3 (17.1, 23.6)17.2 (14.8, 18.5)23.3 (20.1, 30.7)< 0.001< 0.001< 0.001< 0.001
NC mass > 20%a59 (100%)16 (44.4%)< 0.00125 (100%)14 (41.2%)0 (0%)14 (77.8%)< 0.001< 0.0010.025< 0.001
NC mass > 25%a59 (100%)5 (13.9%)< 0.00125 (100%)5 (14.7%)0 (0%)5 (27.8%)< 0.001< 0.001< 0.0010.046
NC mass/BSA (g/m2)b36.1 (32.3, 42.9)13.6 (10.5, 17.2)< 0.00135.1 (30.9, 39.2)12.7 (10.4, 17.0)10.0 (8.8, 11.6)17.0 (15.0, 23.7)< 0.001< 0.001< 0.001< 0.001
NC mass > 15 g/m2a59 (100%)15 (41.7%)< 0.00125 (100%)13 (38.2%)0 (0%)13 (72.2%)< 0.001< 0.0010.009< 0.001
  1. Data presented as n (%) or median (IQR)
  2. NC:C >2.3 = maximum end-diastolic non-compacted (NC): compacted (C) myocardium diameter ratio >2.3 in at least one segment.
  3. CMR cardiovascular magnetic resonance, LVNC left ventricular non-compaction cardiomyopathy, LV left ventricle, NC non-compacted myocardium, C compacted myocardium, BSA body surface area
  4. aFisher’s exact test
  5. bWilcoxon rank sum test