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Table 3 Diagnostic accuracy of CMR to detect obstructive CAD

From: Cardiovascular magnetic resonance accurately detects obstructive coronary artery disease in suspected non-ST elevation myocardial infarction: a sub-analysis of the CARMENTA Trial

 

CMR sequence

Sensitivity (%)

Specificity (%)

Overall accuracy (%)

Step 1

Combination of cine, T2-weighted and LGE (n = 51)

79 (62–91)

71 (44–90)

77 (63–87)

Step 2

Vasodilator stress-perfusion imaging (n = 19)

86 (42–100)

92 (62–100)

90 (67–99)

Step 3

Final analysis

(n = 51)

97 (85–100)

65 (38–86)

86 (74–94)

  1. Numbers are presented as percentages (with 95% confidence intervals)
  2. Obstructive CAD = coronary artery disease (defined as ≥ 70% stenosis in any epicardial coronary artery); LGE = late gadolinium enhancement. Step 1 abnormal: (1) regional wall-motion abnormalities, and/or subendocardial/transmural hyperintensity on T2-weighted and/or LGE in ≥ 2 segments or (2) at least 2 of 3 sequences abnormal in a single segment. Step 2 abnormal (only performed when step 1 was normal or equivocal): persistent subendocardial/transmural perfusion defect in ≥ 2 adjacent segments. Step 3 abnormal: abnormal results step 1 or 2