Table 3 Left atrial parameters and LA longitudinal strain of HCM patients and healthy volunteers
Variable | Healthy subjects (n = 100) | HCM (n = 359) | P | HCM Patients without combined outcome (n = 309) | HCM Patients with combined outcome (n = 50) | P | HCM Patients with LA diameter > 41 mm (n = 135) | HCM Patients with LA diameter ≤ 41 mm (n = 224) | P |
|---|---|---|---|---|---|---|---|---|---|
LA parameters | |||||||||
LA diameter, mm | 29.9 (26.6,33.4) | 40.0 (34.0,45.0) | < 0.001* | 39.0 (34.0,44.0) | 42.0 (37.0,48.0) | < 0.001* | 47.0 (44.0,50.0) | 36.0 (32.0,39.0) | < 0.001* |
LAVI max, ml/m2 | 38.0 (33.1,45.4) | 59.3 (45.0,76.0) | < 0.001* | 56.8 (44.1,72.8) | 68.4 (54.8,89.3) | < 0.001* | 75.3 (60.5,98.7) | 51.4 (41.2,64.5) | < 0.001* |
LAVI p-ac, ml/m2 | 24.4 (20.7,35.6) | 45.4 (33.5,63.1) | < 0.001* | 43.7 (32.1,60.4) | 55.9 (43.5,78.3) | < 0.001* | 64.9 (49.5,83.8) | 38.2 (29.6,49.6) | < 0.001* |
LAVI min, ml/m2 | 15.3 (11.5,18.4) | 31.1 (21.1,45.3) | < 0.001* | 29.3 (20.3,42.6) | 39.8 (27.0,61.4) | < 0.001* | 45.8 (33.1,67.9) | 24.8 (18.3,35.5) | < 0.001* |
Total LAEF, % | 61.4 (56.2,65.8) | 46.3 (37.4,54.5) | < 0.001* | 46.8 ± 12.4 | 37.8 ± 11.5 | < 0.001* | 38.2 (27.0,47.0) | 50.5 (42.8,56.7) | < 0.001* |
Passive LAEF, % | 34.4 (28.1,40.9) | 20.2 (12.6,27.6) | < 0.001* | 21.5 (13.3,28.3) | 15.7 (10.7,21.2) | < 0.001* | 13.9 (9.9,21.3) | 23.1 (17.6,30.8) | < 0.001* |
Active LAEF, % | 41.3 (32.3,48.5) | 31.9 (23.5,39.3) | < 0.001* | 32.3 ± 11.3 | 26.2 ± 10.5 | < 0.001* | 26.4 ± 12.5 | 33.4 ± 10.9 | < 0.001* |
LA longitudinal strain | |||||||||
Reservoir εs, % | 36.1 ± 7.7 | 20.4 ± 7.6 | < 0.001* | 21.7 ± 7.4 | 16.6 ± 5.6 | < 0.001* | 15.6 (11.2,22.5) | 21.9 (17.7,26.7) | < 0.001* |
Conduit εe, % | 20.7 (15.0,24.4) | 8.8 (5.7,13.0) | < 0.001* | 10.0 (6.1,13.4) | 6.6 (4.9,8.1) | < 0.001* | 6.6 (4.8,10.0) | 10.7 (7.1,14.2) | < 0.001* |
Booster εa, % | 15.7 ± 4.1 | 11.0 ± 4.2 | < 0.001* | 11.3 ± 4.1 | 9.9 ± 4.2 | 0.054 | 9.2 (6.1,12.8) | 11.4 (9.2,14.4) | < 0.001* |