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Table 4 Subgroup analysis of repaired tetralogy of Fallot patients

From: Impact of pulmonary valve replacement on left ventricular rotational mechanics in repaired tetralogy of Fallot

Variable

Pre-PVR

Post-PVR

Pre-PVR vs. Post-PVR

TOF-PR (n = 38)

TOF-RVOTO (n = 22)

P-value

TOF-PR (n = 38)

TOF-RVOTO (n = 22)

P-value

TOF-PR P-value

TOF-RVOTO P-value

Heart rate (bpm)

69.4 ± 11.3

80.8 ± 16.0

0.002

67.6 ± 12.1

72.5 ± 15.3

0.173

0.153

0.019

Height (cm)

165.6 ± 11.8

162.0 ± 9.5

0.225

165.6 ± 11.5

162.4 ± 9.0

0.266

1.00

0.675

Weight (kg)

67.2 ± 18.8

60.4 ± 15.7

0.156

70.5 ± 19.9

62.1 ± 14.2

0.089

0.001

0.045

BSA (m2)

1.8 ± 0.3

1.6 ± 0.3

0.138

1.8 ± 0.3

1.7 ± 0.2

0.077

 < 0.001

0.053

RVEDVI (ml/m2)

191.4 ± 29.0

164.8 ± 82.0

0.153

119.1 ± 28.8

143.2 ± 79.8

0.186

 < 0.001

0.003

RVESVI (ml/m2)

98.0 ± 21.7

109.8 ± 75.2

0.478

65.7 ± 23.4

92.7 ± 75.0

0.114

 < 0.001

0.002

RV mass index (g/m2)

34.8 ± 9.4

43.0 ± 20.8

0.098

26.3 ± 7.4

34.6 ± 17.2

0.041

 < 0.001

 < 0.001

LVEDVI (ml/m2)

84.2 ± 14.2

92.3 ± 24.7

0.168

90.8 ± 15.0

95.5 ± 15.3

0.241

 < 0.001

0.514

LVESVI (ml/m2)

36.1 ± 8.3

45.3 ± 17.8

0.031

38.7 ± 9.2

44.3 ± 11.9

0.045

0.032

0.690

LV mass index (g/m2)

51.2 ± 8.9

57.8 ± 15.8

0.085

52.6 ± 10.9

57.5 ± 12.7

0.118

0.336

0.932

RVEF (%)

49.1 ± 5.8

37.5 ± 11.1

 < 0.001

45.9 ± 6.5

40.0 ± 11.2

0.033

0.001

0.170

LVEF (%)

57.3 ± 5.4

52.0 ± 8.9

0.016

57.8 ± 4.6

54.1 ± 7.2

0.036

0.501

0.077

PR (%)

54 ± 8

17 ± 11

 < 0.001

8 ± 13

2 ± 4

0.007

 < 0.001

 < 0.001

QRS (ms)

149 ± 24

150 ± 24

0.824

144 ± 24

150 ± 28

0.377

0.026

0.915

RVOT PG (mm Hg)

13 ± 8

52 ± 19

 < 0.001

17 ± 6

27 ± 19

0.040

0.018

 < 0.001

TR PG (mm Hg)

29 ± 8

69 ± 17

 < 0.001

27 ± 9

53 ± 24

 < 0.001

0.198

0.027

Peak apical rotation (deg)

4.7 ± 3.8

2.8 ± 3.0

0.054

5.0 ± 3.1

3.5 ± 3.4

0.089

0.652

0.372

Peak basal rotation (deg)

− 1.6 ± 2.9

− 1.7 ± 1.8

0.829

− 1.1 ± 1.7

− 1.3 ± 2.0

0.647

0.316

0.438

Twist (deg)

6.7 ± 5.0

4.7 ± 3.4

0.105

6.6 ± 4.0

5.3 ± 5.1

0.271

0.970

0.509

Torsion (deg/cm)

1.0 ± 0.7

0.8 ± 0.5

0.252

1.0 ± 0.6

0.9 ± 0.9

0.709

0.779

0.363

  1. Bold values are statistically significant p-values
  2. Values are mean ± standard deviation. TOF-PR are repaired tetralogy of Fallot (rTOF) patients with a pulmonary regurgitation fraction > 40% and a right ventricular outflow tract peak gradient ≤ 25 mm Hg. TOF-RVOTO are rTOF patients with a PR fraction ≤ 30% and a RVOT peak gradient or tricuspid regurgitation peak gradient ≥ 40 mm Hg. BSA, body surface area; Deg, degrees; rTOF, repaired tetralogy of Fallot; LVEDVi, left-ventricular end-diastolic volume index; LVESVI, left ventricular end-systolic volume index; LVEF, left ventricular ejection fraction; RVESVi, right ventricular end-systolic volume index; RVEF, right ventriuclar ejection fraction; RVESVI, right ventricular end-systolic volume index; PR, pulmonary regurgitation; PVR, pulmonary valve replacement; RV, right ventricular; RVOT PG, right ventricular outflow tract peak gradient; TOF, tetralogy of Fallot; TR, tricuspid regurgitation; TR PG, tricuspid regurgitation peak gradient
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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