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Table 3 Univariable and multivariable linear regression analysis for factors associated with worsening CKD

From: Cardiac biomarkers in chronic kidney disease are independently associated with myocardial edema and diffuse fibrosis by cardiovascular magnetic resonance

Variable

Worsening CKD

Univariable

Multivariable

B (95% CI)

p-value

B (95% CI)

p-value

Hematocrit (%)

− 0.193 (− 0.283 to − 0.103)

< 0.001

NS

NS

hs-CRP (Lg10)

0.085 (− 0.006 to 0.177)

0.068

0.098 (0.009 to 0.185)

0.031

LVEDV index (ml/m2)

0.204 (0.114 to 0.293)

< 0.001

NS

NS

LV mass index (g/m2)

0.208 (0.119 to 0.297)

< 0.001

NS

NS

LVEF (LVEF)

− 0.068 (− 0.159 to 0.023)

0.143

NS

NS

GLS (%)

0.041 (− 0.050 to 0.133)

0.376

NS

NS

LA area (cm2)

0.153 (0.054 to 0.251)

0.002

NS

NS

IVC variation (%)

− 0.341 (− 0.427 to − 0.255)

< 0.001

− 0.242 (− 0.357 to − 0.158)

< 0.001

LGE (presence)

0.024 (− 0.067 to 0.116)

0.600

NS

NS

Native T1 (ms)

0.348 (0.263 to 0.434)

< 0.001

0.125 (0.022 to 0.235)

0.019

Native T2 (ms)

0.385 (0.301 to 0.470)

< 0.001

0.272 (0.164 to 0.374)

< 0.001

  1. Bold indicated p-value < 0.05
  2. eGFR estimated glomerular filtration rate (in units, ml/min/1.73 m2), CI confidence interval, CRP C-reactive protein, EV end-diastolic volume, EF ejection fraction, GLS global longitudinal strain, LV left ventricular, LGE late gadolinium enhancement, IVC inferior vena cava
  3. P-value < 0.05 was considered significant