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Table 5 Intra- and inter-observer measurement variability

From: Quantification of regurgitation in mitral valve prolapse with four-dimensional flow cardiovascular magnetic resonance

   Bland–Altman* ICC CV, %
4D flow CMR indirect method
Intra-observer MV SV − 1.0 (21 to − 23) 0.982 7
  LVOT SV − 1.1 (9 to − 11) 0.979 5
Inter-observer MV SV 0.8 (37 to − 36) 0.938 12
  LVOT SV 1.0 (19 to − 17) 0.919 10
4D flow CMR direct method
Intra-observer MV RVol − 2.7 (14 to − 20) 0.971 17
Inter-observer MV RVol − 3.1 (33 to − 39) 0.868 32
Standard CMR method
Intra-observer LV SV 1.5 (8 to − 5) 0.998 2.5
  Ao FF − 0.1 (3 to − 3) 0.999 1.5
Inter-observer LV SV 2.7 (19 to − 13) 0.989 6
  Ao FF 0.5 (10 to − 9) 0.986 5
2D-PISA method
Intra-observer MV RVol 2.1 (20 to − 16) 0.986 12
Inter-observer MV RVol 3.2 (34 to − 28) 0.959 15
  1. 4D Flow CMR time-resolved, three-dimensional anatomic coverage, three-directional velocity-encoded phase contrast CMR, MV mitral valve, LVOT left ventricle outflow tract, SV stroke volume, RVol regurgitant volume, LV left ventricle, Ao FF aortic forward flow, 2D-PISA, proximal isovelocity surface area, ICC intraclass correlation coefficient, CV coefficient of variation. *Mean difference (2-sided 95% confidence limits of agreement). † All P < 0.001