Patients with known CAD
|
All patients N = 693
|
Patients without MACE N = 648
|
Patients with MACE N = 45
|
*P-value
|
---|
CSBF at rest (mL/min)
|
86.7 ± 32.9
|
84.7 ± 30.9
|
114.7 ± 44.9
|
< 0.001
|
CSBF during ATP infusion (mL/min)
|
236.4 ± 87.4**
|
235.8 ± 88.7**
|
245.3 ± 66.5**
|
0.47
|
ΔCSBF (mL/min)
|
149.7 ± 72.7
|
151.1 ± 73.8
|
130.6 ± 50.9
|
0.068
|
Coronary flow reserve
|
2.84 ± 0.91
|
2.89 ± 0.92
|
2.27 ± 0.60
|
< 0.001
|
Patients with suspected CAD
|
All patients N = 519
|
Patients without MACE N = 472
|
Patients with MACE N = 47
|
*P-value
|
---|
CSBF at rest (mL/min)
|
89.8 ± 37.8
|
86.6 ± 36.7
|
122.2 ± 33.3
|
< 0.001
|
CSBF during ATP infusion (mL/min)
|
242.4 ± 87.4**
|
241.6 ± 90.3**
|
250.2 ± 48.5**
|
0.52
|
ΔCSBF (mL/min)
|
152.6 ± 70.1
|
155.1 ± 72.1
|
127.9 ± 39.2
|
0.011
|
Coronary flow reserve
|
2.85 ± 0.84
|
2.93 ± 0.84
|
2.10 ± 0.40
|
< 0.001
|
- Data are expressed as mean ± SD or number (%)
- *P-values represent the difference between patients with and without MACE. **P < 0.05 vs. CSBF at rest
- ΔCSBF = CSBF during ATP infusion–CSBF at rest
- Coronary flow reserve = CSBF during ATP infusion / CSBF at rest × 100
- ATP adenosine triphosphate, CSBF coronary sinus blood flow, CFR coronary flow reserve, MACE major adverse cardiac events, SD standard deviation