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Table 3 Six multiple regression models: determinants of AF in all HCM patients, and in those with LA diameter < 45mm, indicating a low risk for AF development

From: Incremental value of left atrial booster and reservoir strain in predicting atrial fibrillation in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance study

  Model 1 Model 2 Model 3 Model 4 Model 5 Model 6
  LA diameter LAESV index LA reservoir strain LA conduit strain LA booster strain LAEF
  HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI) HR (95% CI)
All HCM patients, n = 238       
 Age ≥ 55 5.07 (2.23–11.55)** 4.72 (2.06–10.95)** 4.05 (1.73–9.46)** 4.42 (1.76–11.06)** 6.62 (2.79–15.70)** 4.19 (1.80–9.76)**
 LA diameter ≥ 42 mm 1.92 (0.95–3.91)
 LAESV index ≥ 27 mL/m2 1.82 (0.90–3.68)
 LA reservoir strain ≤ 18% 2.56 (1.24–5.27)*
 LA conduit strain ≤ 12% 1.58 (0.58–4.25)
 LA booster strain ≤ 8% 3.69 (1.81–7.52)**
 LAEF ≤ 45% 2.43 (1.20–4.92)*
HCM patients with LA diameter < 45 mm, n = 217       
 Age ≥ 55 4.05 (1.72–9.51)** 4.73 (2.04–10.96)** 3.34 (1.38–8.06)** 3.41 (1.30–8.96)* 5.78 (2.35–14.23)** 3.67 (1.53–8.81)**
 LA diameter ≥ 42 mm 1.94 (0.84–4.47)
 LAESV index ≥ mL/m2 1.82 (0.90–3.68)
 LA reservoir strain ≤ 18% 2.49 (1.13–5.32)*
 LA conduit strain ≤ 12% 1.72 (0.60–4.90)
 LA booster strain ≤ 8% 3.74 (1.70–8.07)**
 LAEF ≤ 45% 1.98 (0.92–4.28)
  1. EF, ejection fraction, HCM, hypertrophic cardiomyopathy, HR, hazard ratio, LA, left atria, LAEDV, left atrial end diastolic volume, LAEF, left atrial ejection fraction
  2. *Indicates a significant difference of P < 0.05
  3. **Indicates a significant difference of P < 0.01