Table 3 Six multiple regression models: determinants of AF in all HCM patients, and in those with LA diameter < 45mm, indicating a low risk for AF development
| Â | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | Model 6 |
|---|---|---|---|---|---|---|
| Â | LA diameter | LAESV index | LA reservoir strain | LA conduit strain | LA booster strain | LAEF |
| Â | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) |
All HCM patients, n = 238 |  |  |  |  |  |  |
 Age ≥ 55 | 5.07 (2.23–11.55)** | 4.72 (2.06–10.95)** | 4.05 (1.73–9.46)** | 4.42 (1.76–11.06)** | 6.62 (2.79–15.70)** | 4.19 (1.80–9.76)** |
 LA diameter ≥ 42 mm | 1.92 (0.95–3.91) | – | – | – | – | – |
 LAESV index ≥ 27 mL/m2 | – | 1.82 (0.90–3.68) | – | – | – | – |
 LA reservoir strain ≤ 18% | – | – | 2.56 (1.24–5.27)* | – | – | – |
 LA conduit strain ≤ 12% | – | – | – | 1.58 (0.58–4.25) | – | – |
 LA booster strain ≤ 8% | – | – | – | – | 3.69 (1.81–7.52)** | – |
 LAEF ≤ 45% | – | – | – | – | – | 2.43 (1.20–4.92)* |
HCM patients with LA diameter < 45 mm, n = 217 |  |  |  |  |  |  |
 Age ≥ 55 | 4.05 (1.72–9.51)** | 4.73 (2.04–10.96)** | 3.34 (1.38–8.06)** | 3.41 (1.30–8.96)* | 5.78 (2.35–14.23)** | 3.67 (1.53–8.81)** |
 LA diameter ≥ 42 mm | 1.94 (0.84–4.47) | – | – | – | – | – |
 LAESV index ≥ mL/m2 | – | 1.82 (0.90–3.68) | – | – | – | – |
 LA reservoir strain ≤ 18% | – | – | 2.49 (1.13–5.32)* | – | – | – |
 LA conduit strain ≤ 12% | – | – | – | 1.72 (0.60–4.90) | – | – |
 LA booster strain ≤ 8% | – | – | – | – | 3.74 (1.70–8.07)** | – |
 LAEF ≤ 45% | – | – | – | – | – | 1.98 (0.92–4.28) |