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Table 5 Univariate and multiple linear regression showing determinants of LA strain in an AF naïve population

From: Incremental value of left atrial booster and reservoir strain in predicting atrial fibrillation in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance study

  Univariate linear regression Multivariable linear regression
  Reservoir strain Conduit strain Booster strain Reservoir strain Conduit strain Booster strain
  β P values β P values β P values β P values β P values β P values
Age, per year  − 0.11  < 0.001*  − 0.19  < 0.001* 0.06  < 0.001*  − 0.10  < 0.001*  − 0.18  < 0.001* 0.04 0.018*
Gender 1.17 0.102 1.45 0.050 0.66 0.196
Systolic blood pressure, per mmHg  − 0.06 0.001*  − 0.07  < 0.001* 0.01 0.567 0.01 0.637  − 0.01 0.891
Diastolic blood pressure, per mmHg  − 0.07 0.027*  − 0.07 0.052  − 0.01 0.599  − 0.04 0.309
Body mass index, per unit  − 0.10 0.120  − 0.16 0.024* 0.06 0.245 0.11 0.095
Hypertension  − 0.52 0.392  − 2.06 0.001* 1.29 0.003* 0.71 0.272 0.01 0.998
Diabetes 0.07 0.951  − 2.36 0.044* 2.00 0.014*  − 0.21 0.834 0.65 0.473
Smoking history 0.31 0.655  − 1.38 0.056 1.59 0.001* 1.33 0.014*
Hypercholesterolemia  − 0.46 0.626  − 2.20 0.024* 1.24 0.066  − 0.21 0.771
Familyhistory of SCD 1st degree relative 0.67 0.566 0.24 0.843 0.68 0.424
Family history of SCD 2nd degree relative 0.56 0.540 0.26 0.786 0.34 0.613
SCD risk score  − 0.24 0.602  − 0.85 0.067 0.56 0.080
VT 0.17 0.864  − 1.19 0.257 1.49 0.038* 1.24 0.093
TIA stroke  − 1.83 0.461  − 1.98 0.442  − 0.17 0.923
Syncope  − 1.40 0.088  − 2.34 0.006* 0.60 0.313  − 0.70 0.376
NYHA class  − 1.84  < 0.001*  − 2.63  < 0.001* 0.35 0.325  − 1.07 0.042*  − 0.52 0.274
LGE, presence/absence  − 2.15 0.012*  − 3.88  < 0.001* 1.33 0.030*  − 0.93 0.256  − 1.86 0.007* 0.71 0.254
LGE, % 0.02 0.561  − 0.05 0.123 0.05 0.028* 0.02 0.368
LGE mass, grams  − 0.03 0.166  − 0.05 0.017* 0.01 0.409  − 0.02 0.186
Presence of sarcomeric variant 0.88 0.166 2.49  < 0.001*  − 1.37 0.002* 0.24 0.722  − 0.72 0.215
Mitral regurgitation  − 3.26 0.001*  − 4.12  < 0.001* 0.16 0.816  − 1.16 0.256  − 2.89 0.001*
LV maximal wall thickness, mm  − 0.32  < 0.001*  − 0.32  < 0.001*  − 0.05 0.386  − 0.20 0.021*  − 0.15 0.052
LV mass, grams  − 0.03  < 0.001*  − 0.02 0.003*  − 0.01 0.068  − 0.01 0.035*  − 0.01 0.030*
LVOT max pressure gradient, mmHg 0.08 0.462  − 0.12 0.282 0.13 0.101
LVOT obstruction ≥ 30 mmHg, n, %  − 0.88 0.271  − 1.01 0.223  − 0.23 0.693
LVEDV index, mL/m2 0.02 0.383 0.06 0.003*  − 0.03 0.028*  − 0.04 0.278  − 0.02 0.370
LVESV index, mL/m2  − 0.03 0.385 0.03 0.452  − 0.05 0.088
LV stroke volume index, mL/m2 0.06 0.050 0.12  < 0.001*  − 0.04 0.055 0.13 0.011*
LV ejection Fraction, % 0.10 0.024* 0.08 0.076 0.02 0.589 0.131 0.002*
  1. LGE late gadolinium enhancement (5-SD), LV left ventricle, LVEDV left ventricular end diastolic volume index, LVESV left ventricular end systolic volume index, LVOT left ventricular outflow tract, LVSV left ventricular stroke volume, NYHA New York heart association, SCD sudden cardiac death, TIA transient ischemic attack, VT ventricular tachycardia
  2. *Indicates a significant difference of P < 0.05