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Table 5 Univariate and multiple linear regression showing determinants of LA strain in an AF naïve population

From: Incremental value of left atrial booster and reservoir strain in predicting atrial fibrillation in patients with hypertrophic cardiomyopathy: a cardiovascular magnetic resonance study

 

Univariate linear regression

Multivariable linear regression

 

Reservoir strain

Conduit strain

Booster strain

Reservoir strain

Conduit strain

Booster strain

 

β

P values

β

P values

β

P values

β

P values

β

P values

β

P values

Age, per year

 − 0.11

 < 0.001*

 − 0.19

 < 0.001*

0.06

 < 0.001*

 − 0.10

 < 0.001*

 − 0.18

 < 0.001*

0.04

0.018*

Gender

1.17

0.102

1.45

0.050

0.66

0.196

–

–

–

–

–

–

Systolic blood pressure, per mmHg

 − 0.06

0.001*

 − 0.07

 < 0.001*

0.01

0.567

0.01

0.637

 − 0.01

0.891

–

–

Diastolic blood pressure, per mmHg

 − 0.07

0.027*

 − 0.07

0.052

 − 0.01

0.599

 − 0.04

0.309

–

–

–

–

Body mass index, per unit

 − 0.10

0.120

 − 0.16

0.024*

0.06

0.245

–

–

0.11

0.095

–

–

Hypertension

 − 0.52

0.392

 − 2.06

0.001*

1.29

0.003*

–

–

0.71

0.272

0.01

0.998

Diabetes

0.07

0.951

 − 2.36

0.044*

2.00

0.014*

–

–

 − 0.21

0.834

0.65

0.473

Smoking history

0.31

0.655

 − 1.38

0.056

1.59

0.001*

–

–

–

–

1.33

0.014*

Hypercholesterolemia

 − 0.46

0.626

 − 2.20

0.024*

1.24

0.066

–

–

 − 0.21

0.771

–

–

Familyhistory of SCD 1st degree relative

0.67

0.566

0.24

0.843

0.68

0.424

–

–

–

–

–

–

Family history of SCD 2nd degree relative

0.56

0.540

0.26

0.786

0.34

0.613

–

–

–

–

–

–

SCD risk score

 − 0.24

0.602

 − 0.85

0.067

0.56

0.080

–

–

–

–

–

–

VT

0.17

0.864

 − 1.19

0.257

1.49

0.038*

–

–

–

–

1.24

0.093

TIA stroke

 − 1.83

0.461

 − 1.98

0.442

 − 0.17

0.923

–

–

–

–

–

–

Syncope

 − 1.40

0.088

 − 2.34

0.006*

0.60

0.313

–

–

 − 0.70

0.376

–

–

NYHA class

 − 1.84

 < 0.001*

 − 2.63

 < 0.001*

0.35

0.325

 − 1.07

0.042*

 − 0.52

0.274

–

–

LGE, presence/absence

 − 2.15

0.012*

 − 3.88

 < 0.001*

1.33

0.030*

 − 0.93

0.256

 − 1.86

0.007*

0.71

0.254

LGE, %

0.02

0.561

 − 0.05

0.123

0.05

0.028*

–

–

–

–

0.02

0.368

LGE mass, grams

 − 0.03

0.166

 − 0.05

0.017*

0.01

0.409

–

–

 − 0.02

0.186

–

–

Presence of sarcomeric variant

0.88

0.166

2.49

 < 0.001*

 − 1.37

0.002*

–

–

0.24

0.722

 − 0.72

0.215

Mitral regurgitation

 − 3.26

0.001*

 − 4.12

 < 0.001*

0.16

0.816

 − 1.16

0.256

 − 2.89

0.001*

–

–

LV maximal wall thickness, mm

 − 0.32

 < 0.001*

 − 0.32

 < 0.001*

 − 0.05

0.386

 − 0.20

0.021*

 − 0.15

0.052

–

–

LV mass, grams

 − 0.03

 < 0.001*

 − 0.02

0.003*

 − 0.01

0.068

 − 0.01

0.035*

 − 0.01

0.030*

–

–

LVOT max pressure gradient, mmHg

0.08

0.462

 − 0.12

0.282

0.13

0.101

–

–

–

–

–

–

LVOT obstruction ≥ 30 mmHg, n, %

 − 0.88

0.271

 − 1.01

0.223

 − 0.23

0.693

–

–

–

–

–

–

LVEDV index, mL/m2

0.02

0.383

0.06

0.003*

 − 0.03

0.028*

–

–

 − 0.04

0.278

 − 0.02

0.370

LVESV index, mL/m2

 − 0.03

0.385

0.03

0.452

 − 0.05

0.088

–

–

–

–

–

–

LV stroke volume index, mL/m2

0.06

0.050

0.12

 < 0.001*

 − 0.04

0.055

–

–

0.13

0.011*

–

–

LV ejection Fraction, %

0.10

0.024*

0.08

0.076

0.02

0.589

0.131

0.002*

–

–

–

–

  1. LGE late gadolinium enhancement (5-SD), LV left ventricle, LVEDV left ventricular end diastolic volume index, LVESV left ventricular end systolic volume index, LVOT left ventricular outflow tract, LVSV left ventricular stroke volume, NYHA New York heart association, SCD sudden cardiac death, TIA transient ischemic attack, VT ventricular tachycardia
  2. *Indicates a significant difference of P < 0.05
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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