Table 1 Characteristics of participants before and after 18 weeks’ antihypertensive treatment

Office systolic BP (mmHg)

174 ± 15.7

132 ± 11.9

 < 0.001

Office diastolic BP (mmHg)

103 ± 9.3

80 ± 8.4

 < 0.001

Daytime average systolic BP (mmHg)

163 ± 10.4

134 ± 10.4

 < 0.001

Daytime average diastolic BP (mmHg)

93 ± 8.9

78 ± 6.8

 < 0.001

Heart rate (bpm)

71 ± 12.0

64 ± 10.1

 < 0.001^a

BMI (kg/m²)

29.7 ± 5.3

29.7 ± 4.9

0.9

Current smoker (n)

5 (12%)

5 (12%)

1.0^b

Alcohol (units/week)

8 (1–18)

9 (1–15)

0.8^a

Fasting total cholesterol (mmol/L)

5.6 ± 1.2

5.6 ± 1.3

0.7

Creatinine (μmol/L)

75 ± 13.0

78 ± 13.4

0.3

HbA1c (mmol/mol)

38 ± 0.5

38 ± 0.6

0.6

Angiotensin receptor blocker (n)

0

37 (90%)

n/a

Calcium channel blocker (n)

0

40 (98%)

n/a

Thiazide diuretic (n)

0

24 (59%)

n/a

Aldosterone antagonist (n)

0

9 (21%)

n/a

α-blocker (n)

0

1 (2%)

n/a

β-blocker (n)

0

3 (7%)

n/a

Number of anti-hypertensives (n)

0

3 (2–3)

n/a