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Table 3 Cox proportional hazards regression analysis for the association between clinical and CMR strain parameters and time to first appropriate ICD shock or all-cause mortality, or time to all-cause mortality, stratified by primary and secondary prevention indication*

From: Myocardial strain assessment using cardiovascular magnetic resonance imaging in recipients of implantable cardioverter defibrillators

Strain parameter

Adjusted HR per 1% higher value (95% CI)

p value

Stratified analysis

Primary prevention

Secondary prevention

Appropriate ICD shock or all-cause mortality

 GLS

1.07 (1.02–1.11)

0.003

1.14 (1.04–1.24)

1.05 (1.00–1.10)

 GCS

1.06 (1.01–1.10)

0.008

1.05 (0.98–1.12)

1.07 (1.01–1.12)

 GRS

0.97 (0.95–0.99)

0.012

0.96 (0.93–1.00)

0.98 (0.95–1.00)

All-cause mortality

 GLS

1.08 (1.03–1.13)

0.002

1.15 (1.01–1.31)

1.05 (1.00–1.10)

 GCS

1.10 (1.03–1.17)

0.003

1.06 (0.98–1.16)

1.17 (1.08–1.26)

 GRS

0.94 (0.90–0.98)

0.004

0.96 (0.89–1.02)

0.92 (0.88–0.97)

  1. *Adjusted for age, primary prevention, ischemic heart disease, presence of late gadolinium enhancement. There was no significant interaction (all p interaction > 0.10) between primary/secondary prevention and any of the LV strain parameters
  2. GLS global longitudinal strain, GCS global circumferential strain, GRS global circumferential strain